Methicillin-resistant Staphylococcus aureus: an overview of basic and clinical research

NA Turner, BK Sharma-Kuinkel… - Nature Reviews …, 2019 - nature.com
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the most successful modern
pathogens. The same organism that lives as a commensal and is transmitted in both health …

Staphylococcus aureus infections: epidemiology, pathophysiology, clinical manifestations, and management

SYC Tong, JS Davis, E Eichenberger… - Clinical microbiology …, 2015 - Am Soc Microbiol
Staphylococcus aureus is a major human pathogen that causes a wide range of clinical
infections. It is a leading cause of bacteremia and infective endocarditis as well as …

Daptomycin

M Heidary, AD Khosravi, S Khoshnood… - Journal of …, 2018 - academic.oup.com
Daptomycin is a cyclic lipopeptide antibiotic used for the treatment of Gram-positive
infections including complicated skin and skin structure infections, right-sided infective …

Daptomycin Plus Fosfomycin Versus Daptomycin Alone for Methicillin-resistant Staphylococcus aureus Bacteremia and Endocarditis: A Randomized Clinical Trial

M Pujol, JM Miró, E Shaw, JM Aguado… - Clinical Infectious …, 2021 - academic.oup.com
Background We aimed to determine whether daptomycin plus fosfomycin provides higher
treatment success than daptomycin alone for methicillin-resistant Staphylococcus aureus …

Persistent methicillin-Resistant Staphylococcus aureus Bacteremia: Resetting the Clock for Optimal Management

TL Holland, AS Bayer… - Clinical Infectious Diseases, 2022 - academic.oup.com
A positive follow-up blood culture for methicillin-resistant Staphylococcus aureus (MRSA)
while on seemingly appropriate therapy is a common and ominous development. However …

Persistent Methicillin-Resistant Staphylococcus aureus Bacteremia: Host, Pathogen, and Treatment

JB Parsons, AC Westgeest, BP Conlon, VG Fowler Jr - Antibiotics, 2023 - mdpi.com
Methicillin-resistant Staphylococcus aureus (MRSA) is a devastating pathogen responsible
for a variety of life-threatening infections. A distinctive characteristic of this pathogen is its …

Contemporary Management of Staphylococcus aureus Bacteremia—Controversies in Clinical Practice

DJ Minter, A Appa, HF Chambers… - Clinical Infectious …, 2023 - academic.oup.com
Staphylococcus aureus bacteremia (SAB) carries a high risk for excess morbidity and
mortality. Despite its prevalence, significant practice variation continues to permeate clinical …

Insights and clinical perspectives of daptomycin resistance in Staphylococcus aureus: a review of the available evidence

S Stefani, F Campanile, M Santagati… - International journal of …, 2015 - Elsevier
The emergence of glycopeptide reduced susceptibility and resistance in Staphylococcus
aureus strains is a growing clinical problem that poses significant clinical challenges in …

Treatment of methicillin-resistant Staphylococcus aureus: vancomycin and beyond

NE Holmes, SYC Tong, JS Davis… - Seminars in respiratory …, 2015 - thieme-connect.com
There has been a welcome increase in the number of agents available for the treatment of
methicillin-resistant Staphylococcus aureus (MRSA). Vancomycin remains an acceptable …

Investigational drugs to treat methicillin-resistant Staphylococcus aureus

C Vuong, AJ Yeh, GYC Cheung… - Expert opinion on …, 2016 - Taylor & Francis
Introduction: Staphylococcus aureus remains one of the leading causes of morbidity and
mortality worldwide. This is to a large extent due to antibiotic-resistant strains, in particular …