Fibrosis is an intrinsic response to chronic injury, maintaining organ integrity when extensive
necrosis or apoptosis occurs. With protracted damage, fibrosis can progress toward …

Liver resection causes marked perfusion alterations in the liver remnant both on the organ
scale (vascular anatomy) and on the microscale (sinusoidal blood flow on tissue level) …

Diagnostic 13 C-stable isotope probes are currently being expanded in their scope, to
provide precise evaluations of the presence or absence of etiologically significant changes …

Assessment of the liver function, and the need of constant monitoring of the organ's capacity,
concerns not only patients with primary liver diseases, but also those at risk of hepatopathies …

Up to 30% of patients with hepatitis C virus (HCV) infection and normal serum alanine
aminotransferase (NALT) have significant liver disease. Currently, many of these patients …

Abstract 13 C-Liver-function breath tests have been used in clinical diagnostics and, to a
limited extent, to investigate hepatic function. From a practical perspective, tests such as the …

Interindividual variability in the expression and function of drug metabolizing cytochrome P
(CYP) 450 enzymes, determined by a combination of genetic, non-genetic and …

AIM: To assess the role of the 13 C-methacetin breath test (MBT) in patients with acute liver
disease. METHODS: Fifteen patients with severe acute liver disease from diverse etiologies …

Background The 13C‐methacetin breath test (MBT) has been proposed for the non‐invasive
evaluation of hepatic microsomal activity. Aim To test a new continuous breath analysis …

Background MELD score and MELD score derivates are used to objectify and grade the risk
of liver-related death in patients with liver cirrhosis. We recently proposed a new predictive …