In Silico Study of the Potential of Brazilein Sappan Wood as a Beta-Lactamase Inhibitor against Extended-Spectrum Beta-Lactamase-Encoding Genes

D Krihariyani, ED Woelansari… - … Journal of Medical …, 2024 - pmc.ncbi.nlm.nih.gov
Background Infectious illnesses are a serious health concern in Indonesia. Widespread use
of self-medication by the community increases the risk of developing multi-drug resistant …

Thiourea Derivatives as Estrogen Receptor Alpha Inhibitors for Breast Cancer Therapy: An In Silico Evaluation with ADMET Prediction and Molecular Docking

H Puspaweni, BT Purwanto, T Widiandani… - Borneo Journal of …, 2024 - journal.umpr.ac.id
Breast cancer remains a significant public health concern, necessitating the discovery of
novel therapeutic agents. This study investigates the potential of thiourea derivatives …

[PDF][PDF] Anticancer activity of Aucklandia costus Falc. terpenes: Targeting MDM2 protein inhibition for therapeutic advancements

CO Raharjo, CS Akbar, MQ Rahmalia - Journal of Pharmacy & …, 2024 - jppres.com
Abstract Context: Protein 53 (p53) is a well-known tumor suppressor protein, while murine
double minute 2 (MDM2) acts as a negative regulator of p53, leading to p53 inactivation and …

In silico investigation of tropical natural product for wild-type and quadrupole mutant PfDHFR inhibitors as antimalarial candidates

PJP Tjitda, FO Nıtbanı, AA Parıkesıt, MIT Bessı… - Tropical Journal of …, 2024 - ajol.info
Plasmodium falciparum dihydrofolate reductase (PfDHFR) is an essential enzyme in the
development of parasitic DNA and its inhibition often leads to the impediment of parasite …

[PDF][PDF] In-silico ANALYSIS OF (S)-PINOSTROBINBENZOATE DERIVATIVES FROM Boesenbergia pandurata Roxb. AS THE CYCLOOXYGENASE-2 INHIBITORS IN …

AS Wiyono, NW Diyah… - Rasayan Journal of …, 2024 - rasayanjournal.co.in
ABSTRACT Boesenbergia pandurata Roxb. Schlecht, often known as Temu kunci, contains
the flavonoid pinostrobin in its rhizome. It is useful against inflammation because it can …

Quantitative Structure-Activity Relationship (QSAR) Of N-Benzoyl-N'-Phenylthiourea Compound And Derivatives In Mcf-7 Cancer Cells

D Kesuma, H Santosa, AL Nasyanka… - RASĀYAN Journal of …, 2021 - repository.ubaya.ac.id
Thiourea derivatives are one of the promising anticancer groups to be developed further.
These derivatives act as an EGFR inhibitor by inhibiting Tyrosine Kinase Receptors (RTKs) …

Studi in silico: Hubungan Kuantitatif Struktur-Aktivitas Antivirus SARS-COV2 Pada Senyawa Turunan N-4-benzoil-N'-(4-fluorofenil) tiourea

AL Nasyanka, D Ratnasari, J Na'imah… - … Syifa Sciences and …, 2022 - repository.ubaya.ac.id
Terapi spesifik untuk virus SARS-COV2 masih dikembangkan dibeberapa negara di dunia.
Salah satu target molekuler yang diduga spesifik pada SARS COV2 adalah 3CLpro atau …

Studi In silico: Toksisitas Senyawa Potensial Sebagai Antikanker Turunan N-((4-Fluorofenil) Karbamatiol) Benzamida

AL Nasyanka, D Ratnasari… - … Medika (J-PhAM …, 2023 - jurnal.stikesrsanwarmedika.ac.id
Senyawa potensial turunan N-((4-Fluorofenil) Karbamatiol) Benzamida telah diprediksi
mempunyai aktivitas yang baik pada reseptor sirtuin-1 yang berperan dalam pemicu kanker …

In silico investigations of triazole-trimethoxyphenyl hybrids as anti-proliferative agents against adenocarcinomic human alveolar basal epithelial cells (A549): DFT …

AO Sunday, S Abdullahi, OK Gabriel, OE Moses… - 2024 - researchsquare.com
Twenty-eight sets of synthesized triazole-trimethoxyphenyl hybrids (TPD) were considered
as anti-proliferative drugs against human alveolar basal epithelial (A549) cancer cell lines …

[引用][C] In Silico Study Anti-Inflammatory of Active Compound of Ramania Leaves Extract (Bouea macrophylla Griffith) Against Protein Kinase C-β

I Taufiqurrahman, SA Rahma, I Erlita, JP Utami… - Seybold Report Journal