Although most patients with chronic pain are women, the preclinical literature regarding pain
processing and the pathophysiology of chronic pain has historically been derived …

Chronic pain is a common, complex, and distressing problem that has a profound impact on
individuals and society. It frequently presents as a result of a disease or an injury; however, it …

BACKGROUND Primary dysmenorrhea, or painful menstruation in the absence of pelvic
pathology, is a common, and often debilitating, gynecological condition that affects between …

In humans, the combination of all sex-specific genetic, epigenetic, and hormonal influences
of biologic sex produces different in vivo environments for male and female cells. We dissect …

Recent years have witnessed substantially increased research regarding sex differences in
pain. The expansive body of literature in this area clearly suggests that men and women …

There is much evidence to suggest that gender is an important factor in the modulation of
pain. Literature data strongly suggest that men and women differ in their responses to pain …

Differences in the prevalence of chronic pain in women vs. men are well known, and
decades of laboratory experimentation have demonstrated that women are more sensitive to …

Millions of people are affected by pain-related conditions worldwide. Literature has
consistently shown that each individual experiences and perceives pain in a unique manner …

The purpose of this systematic review was to summarize and critically appraise the results of
10years of human laboratory research on pain and sex/gender. An electronic search …

Sex-related influences on pain and analgesia have become a topic of tremendous scientific
and clinical interest, especially in the last 10 to 15 years. Members of our research group …