[PDF][PDF] The within-host evolution of antimicrobial resistance in Mycobacterium tuberculosis
RAD Castro, S Borrell, S Gagneux - FEMS microbiology reviews, 2021 - academic.oup.com
Tuberculosis (TB) has been responsible for the greatest number of human deaths due to an
infectious disease in general, and due to antimicrobial resistance (AMR) in particular. The …
infectious disease in general, and due to antimicrobial resistance (AMR) in particular. The …
Sweepstakes reproductive success via pervasive and recurrent selective sweeps
Highly fecund natural populations characterized by high early mortality abound, yet our
knowledge about their recruitment dynamics is somewhat rudimentary. This knowledge gap …
knowledge about their recruitment dynamics is somewhat rudimentary. This knowledge gap …
How does evolution work in superabundant microbes?
DA Filatov, M Kirkpatrick - Trends in Microbiology, 2024 - cell.com
Marine phytoplankton play crucial roles in the Earth's ecological, chemical, and geological
processes. They are responsible for about half of global primary production and drive the …
processes. They are responsible for about half of global primary production and drive the …
Interpreting the pervasive observation of U-shaped Site Frequency Spectra
The standard neutral model of molecular evolution has traditionally been used as the null
model for population genomics. We gathered a collection of 45 genome-wide site frequency …
model for population genomics. We gathered a collection of 45 genome-wide site frequency …
Simultaneous inference of past demography and selection from the ancestral recombination graph under the beta coalescent
K Korfmann, TPP Sellinger, F Freund… - Peer Community …, 2024 - peercommunityjournal.org
The reproductive mechanism of a species is a key driver of genome evolution. The standard
Wright-Fisher model for the reproduction of individuals in a population assumes that each …
Wright-Fisher model for the reproduction of individuals in a population assumes that each …
Inference of coalescence times and variant ages using convolutional neural networks
Accurate inference of the time to the most recent common ancestor (TMRCA) between pairs
of individuals and of the age of genomic variants is key in several population genetic …
of individuals and of the age of genomic variants is key in several population genetic …
Genealogical structure changes as range expansions transition from pushed to pulled
G Birzu, O Hallatschek… - Proceedings of the …, 2021 - National Acad Sciences
Range expansions accelerate evolution through multiple mechanisms, including gene
surfing and genetic drift. The inference and control of these evolutionary processes …
surfing and genetic drift. The inference and control of these evolutionary processes …
Population Genomic Evidence for a Repeated Introduction and Rapid Expansion of the Fungal Maize Pathogen Setosphaeria turcica in Europe
M Vidal-Villarejo, F Freund, H Hanekamp… - Genome Biology and …, 2023 - academic.oup.com
Modern agricultural practices, climate change, and globalization foster the rapid spread of
plant pathogens, such as the maize fungal pathogen Setosphaeria turcica, which causes …
plant pathogens, such as the maize fungal pathogen Setosphaeria turcica, which causes …
Determinants of rapid adaptation in species with large variance in offspring production
K Korfmann, M Temple‐Boyer, T Sellinger… - Molecular …, 2024 - Wiley Online Library
The speed of population adaptation to changing biotic and abiotic environments is
determined by the interaction between genetic drift, positive selection and linkage effects …
determined by the interaction between genetic drift, positive selection and linkage effects …
How do monomorphic bacteria evolve? The Mycobacterium tuberculosis complex and the awkward population genetics of extreme clonality
C Stritt, S Gagneux - Peer Community Journal, 2023 - peercommunityjournal.org
Exchange of genetic material through sexual reproduction or horizontal gene transfer is
ubiquitous in nature. Among the few outliers that rarely recombine and mainly evolve by de …
ubiquitous in nature. Among the few outliers that rarely recombine and mainly evolve by de …