Dietary gallic acid as an antioxidant: A review of its food industry applications, health benefits, bioavailability, nano-delivery systems, and drug interactions

Z Xiang, H Guan, X Zhao, Q Xie, Z Xie, F Cai… - Food Research …, 2024 - Elsevier
Gallic acid (GA), a dietary phenolic acid with potent antioxidant activity, is widely distributed
in edible plants. GA has been applied in the food industry as an antimicrobial agent, food …

Biocompatible solvents and ionic liquid-based surfactants as sustainable components to formulate environmentally friendly organized systems

N Dib, CMO Lépori, NM Correa, JJ Silber, RD Falcone… - Polymers, 2021 - mdpi.com
In this review, we deal with the formation and application of biocompatible water-in-oil
microemulsions commonly known as reverse micelles (RMs). These RMs are extremely …

Polymeric versus lipid nanocapsules for miconazole nitrate enhanced topical delivery: in vitro and ex vivo evaluation

RS Abdel-Rashid, DA Helal, AA Alaa-Eldin… - Drug Delivery, 2022 - Taylor & Francis
Nanocapsules can be equated to other nanovesicular systems in which a drug is entrapped
in a void containing liquid core surrounded by a coat. The objective of the present study was …

Statistical optimization of hyaluronic acid enriched ultradeformable elastosomes for ocular delivery of voriconazole via Box-Behnken design: in vitro characterization …

AM Fahmy, M Hassan, DA El-Setouhy, SA Tayel… - Drug …, 2021 - Taylor & Francis
Voriconazole (VCZ) is a well-known broad spectrum triazole antifungal, mainly used orally
and intravenously. The study aimed to formulate VCZ into ultradeformable elastosomes for …

Development and assessment of phospholipid-based luteolin-loaded lipid nanocapsules for skin delivery

M Elmowafy, K Shalaby, MH Elkomy… - International Journal of …, 2022 - Elsevier
Luteolin is an excellent flavone possessing several beneficial properties such as antioxidant
and anti-inflammatory effects which are interesting for skin delivery. Development of an …

Zein/phospholipid composite nanoparticles for successful delivery of gallic acid into ahscs: Influence of size, surface charge, and vitamin a coupling

SAA Radwan, WH El-Maadawy, C Yousry… - International journal …, 2020 - Taylor & Francis
Purpose Zein/phospholipid composite nanoparticles (CNPs) were developed as a delivery
platform for gallic acid (GA), a polyphenolic compound with reported preclinical antifibrotic …

Ashwagandha-loaded nanocapsules improved the behavioral alterations, and blocked MAPK and induced Nrf2 signaling pathways in a hepatic encephalopathy rat …

HMA Khalil, IA Khalil, AK Al-Mokaddem… - Drug Delivery and …, 2023 - Springer
Ashwagandha (ASH), a vital herb in Ayurvedic medicine, demonstrated potent preclinical
hepato-and neuroprotective effects. However, its efficacy is limited due to low oral …

Gallic acid improves liver cirrhosis by reducing oxidative stress and fibrogenesis in the liver of rats induced by bile duct ligation

L Jafaripour, B Sohrabi Zadeh… - Scandinavian journal …, 2023 - Taylor & Francis
Disturbance in the production and excretion of bile acid causes cholestatic liver disease.
Liver cirrhosis is a disease that occurs if cholestasis continues. This study evaluated the …

[HTML][HTML] Emerging and advanced drug delivery systems for improved biopharmaceutical attributes of gallic acid: A review

S Shukla, B Singh, A Singh, C Singh - Phytomedicine Plus, 2022 - Elsevier
Abstract Background Nearly 40–70% of the drug molecules in clinical drug development
suffer from bioavailability issues attributed to poor solubility and absorption. Evidence …

Enhancing the stability, BBB permeability and neuroprotective activity of verbascoside in vitro using lipid nanocapsules in combination with menthol

L Wu, W Huang, K Peng, Y Wang, Q Chen, B Lu - Food Chemistry, 2023 - Elsevier
Verbascoside (VER) shows promising neuroprotective activity. However, the instability and
low permeability in crossing the blood–brain barrier (BBB) greatly hinder its application. In …