Advances and challenges in diagnostics of toxoplasmosis in HIV-infected patients
R Wesołowski, M Pawłowska, M Smoguła… - Pathogens, 2023 - mdpi.com
Toxoplasma gondii is a worldwide distributed protozoan parasite. This apicomplexan
parasite infects one-third of the population worldwide, causing toxoplasmosis, considered …
parasite infects one-third of the population worldwide, causing toxoplasmosis, considered …
Modulation of autophagy as a therapeutic strategy for Toxoplasma gondii infection
A Cheng, H Zhang, B Chen, S Zheng… - Frontiers in Cellular …, 2022 - frontiersin.org
Toxoplasma gondii infection is a severe health threat that endangers billions of people
worldwide. T. gondii utilizes the host cell membrane to form a parasitophorous vacuole (PV) …
worldwide. T. gondii utilizes the host cell membrane to form a parasitophorous vacuole (PV) …
Metabolic changes in Toxoplasma gondii-infected host cells measured by autofluorescence imaging
Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular
parasite that infects warm-blooded vertebrates across the world. In humans, seropositivity …
parasite that infects warm-blooded vertebrates across the world. In humans, seropositivity …
Iron-overload-induced ferroptosis in mouse cerebral toxoplasmosis promotes brain injury and could be inhibited by Deferiprone
C Wang, L Xie, Y Xing, M Liu, J Yang… - PLOS Neglected …, 2023 - journals.plos.org
Iron is a trace metal element that is essential for the survival of cells and parasites. The role
of iron in cerebral toxoplasmosis (CT) is still unclear. Deferiprone (DFP) is the orally active …
of iron in cerebral toxoplasmosis (CT) is still unclear. Deferiprone (DFP) is the orally active …
Immunomodulatory, Antioxidant, and Anti-Inflammatory Activities of Green Synthesized Copper Nanoparticles for Treatment of Chronic Toxoplasma gondii Infection
AD Alanazi, SF Alnomasy - Pharmaceuticals, 2023 - mdpi.com
Background: Nowadays, interest in the use of nanotechnology for medical purposes is
increasing. The current experimental investigation is planned for the green synthesis …
increasing. The current experimental investigation is planned for the green synthesis …
Mitochondria-selective dicationic small-molecule ligand targeting G-quadruplex structures for human colorectal cancer therapy
BX Zheng, W Long, W Zheng, Y Zeng… - Journal of medicinal …, 2024 - ACS Publications
Mitochondria are important drug targets for anticancer and other disease therapies. Certain
human mitochondrial DNA sequences capable of forming G-quadruplex structures (G4s) are …
human mitochondrial DNA sequences capable of forming G-quadruplex structures (G4s) are …
Toxoplasma gondii infection affects the complete blood count and disturbs the markers of oxidative stress from the vital organs of wild rodents
Rodents are the synanthropic mammals that are existing in close proximity to humans and
their belongings and have the potential to act as the reservoir for a variety of parasites …
their belongings and have the potential to act as the reservoir for a variety of parasites …
[HTML][HTML] Molecular modelling and experimental validation identified a new therapeutic inhibitor of toxoplasmosis
OS Adeyemi, T Johnson, T Maduakolam-Aniobi… - Computers in Biology …, 2024 - Elsevier
Toxoplasmosis is a widespread parasitic disease, caused by Toxoplasma gondii, that affects
nearly one-third of the human population. The lack of effective treatments drives the demand …
nearly one-third of the human population. The lack of effective treatments drives the demand …
Strategies of pathogens to escape from NO-based host defense
G De Simone, A di Masi, P Ascenzi - Antioxidants, 2022 - mdpi.com
Nitric oxide (NO) is an essential signaling molecule present in most living organisms
including bacteria, fungi, plants, and animals. NO participates in a wide range of biological …
including bacteria, fungi, plants, and animals. NO participates in a wide range of biological …
Biogenic selenium nanoparticles: trace element with promising anti-toxoplasma effect
FM Arafa, NMFH Mogahed… - Pathogens and Global …, 2023 - Taylor & Francis
Toxoplasmosis is an opportunistic infection caused by the coccidian Toxoplasma gondii
which represents a food and water contaminant. The available chemotherapeutic agents for …
which represents a food and water contaminant. The available chemotherapeutic agents for …