Swine influenza A viruses and the tangled relationship with humans

TK Anderson, J Chang… - Cold Spring …, 2021 - perspectivesinmedicine.cshlp.org
Influenza A viruses (IAVs) are the causative agents of one of the most important viral
respiratory diseases in pigs and humans. Human and swine IAV are prone to interspecies …

Antigenic characterization of influenza and SARS-CoV-2 viruses

Y Wang, CY Tang, XF Wan - Analytical and Bioanalytical Chemistry, 2022 - Springer
Antigenic characterization of emerging and re-emerging viruses is necessary for the
prevention of and response to outbreaks, evaluation of infection mechanisms …

Detection of live attenuated influenza vaccine virus and evidence of reassortment in the US swine population

A Sharma, MA Zeller, G Li, KM Harmon… - Journal of …, 2020 - journals.sagepub.com
Influenza vaccines historically have been multivalent, whole virus inactivated products. The
first bivalent, intranasal, live attenuated influenza vaccine (LAIV; Ingelvac Provenza), with …

The genomic landscape of swine influenza A viruses in Southeast Asia

MA Zeller, J Ma, FY Wong, S Tum… - Proceedings of the …, 2023 - National Acad Sciences
Swine are a primary source for the emergence of pandemic influenza A viruses. The
intensification of swine production, along with global trade, has amplified the transmission …

A systematic review analyzing the prevalence and circulation of influenza viruses in swine population worldwide

RP Chauhan, ML Gordon - Pathogens, 2020 - mdpi.com
The global anxiety and a significant threat to public health due to the current COVID-19
pandemic reiterate the need for active surveillance for the zoonotic virus diseases of …

octoFLU: automated classification for the evolutionary origin of influenza A virus gene sequences detected in US Swine

J Chang, TK Anderson, MA Zeller… - Microbiology …, 2019 - Am Soc Microbiol
The diversity of the 8 genes of influenza A viruses (IAV) in swine reflects introductions from
nonswine hosts and subsequent antigenic drift and shift. Here, we curated a data set and …

2018-2019 human seasonal H3N2 influenza A virus spillovers into swine with demonstrated virus transmission in pigs were not sustained in the pig population

JD Powell, MN Thomas, TK Anderson… - Journal of …, 2024 - journals.asm.org
Human seasonal H3 clade 3C3a influenza A viruses (IAV) were detected four times in US
pigs from commercial swine farms in Michigan, Illinois, and Virginia in 2019. To evaluate the …

Reverse zoonosis of the 2022–2023 human seasonal H3N2 detected in swine

MA Zeller, D Carnevale de Almeida Moraes… - npj Viruses, 2024 - nature.com
Abstract The Iowa State University Veterinary Diagnostic Laboratory detected nineteen
human-to-swine reverse zoonoses of the 2022–2023 human seasonal H3N2 between …

Evolution and antigenic advancement of N2 neuraminidase of swine influenza A viruses circulating in the United States following two separate introductions from …

BS Kaplan, TK Anderson, J Chang, J Santos… - Journal of …, 2021 - Am Soc Microbiol
Two separate introductions of human seasonal N2 neuraminidase genes were sustained in
US swine since 1998 (N2-98) and 2002 (N2-02). Herein, we characterized the antigenic …

Antigenic distance between North American swine and human seasonal H3N2 influenza A viruses as an indication of zoonotic risk to humans

CK Souza, TK Anderson, J Chang, D Venkatesh… - Journal of …, 2022 - Am Soc Microbiol
Human-to-swine transmission of influenza A virus (IAV) repeatedly occurs, leading to
sustained transmission and increased diversity in swine; human seasonal H3N2 …