Generations of genomes: advances in paleogenomics technology and engagement for Indigenous people of the Americas

KS Tsosie, RL Begay, K Fox, G Nanibaa'A - Current opinion in genetics & …, 2020 - Elsevier
For decades, scientists have collected genomic information from Indigenous peoples and
their ancestors with the goal of elucidating human migration events, understanding ancestral …

Personalized medicine and nutrition in hepatology for preventing chronic liver disease in Mexico

A Panduro, S Roman, IM Mariscal-Martinez… - Frontiers in …, 2024 - frontiersin.org
Chronic liver disease is a global health issue. Patients with chronic liver disease require a
fresh approach that focuses on the genetic and environmental factors that contribute to …

[HTML][HTML] The immunogenetic diversity of the HLA system in Mexico correlates with underlying population genetic structure

R Barquera, DI Hernández-Zaragoza… - Human Immunology, 2020 - Elsevier
We studied HLA class I (HLA-A,-B) and class II (HLA-DRB1,-DQB1) allele groups and alleles
by PCR-SSP based typing in a total of 15,318 mixed ancestry Mexicans from all the states of …

Distributions of the HLA-A, HLA-B, HLA-C, HLA-DRB1, and HLA-DQB1 alleles and haplotype frequencies of 1763 stem cell donors in the Colombian Bone Marrow …

DG Hernández-Mejía, IA Páez-Gutiérrez… - Frontiers in …, 2023 - frontiersin.org
The HLA compatibility continues to be the main limitation when finding compatible donors,
especially if an identical match is not found within the patient's family group. The creation of …

HLA molecular study of patients in a public kidney transplant program in Guatemala

K Escobar-Castro, DI Hernández-Zaragoza… - Human Immunology, 2022 - Elsevier
Guatemala is a country located in Central America, and while it is one of the most populated
countries in the region, the genetic diversity of the population has been poorly analyzed …

[HTML][HTML] Next generation sequencing and the classical HLA loci in full heritage Pima Indians of Arizona: defining the core HLA variation for North American Paleo …

RC Williams, WC Knowler, AR Shuldiner, N Gosalia… - Human Immunology, 2019 - Elsevier
Abstract The Pima Indians of the Gila River Indian Community in Arizona have participated
in a long-range study of type 2 diabetes mellitus since 1965 and have been the subject of …

Differential admixture, human leukocyte antigen diversity, and hematopoietic cell transplantation in Latin America: challenges and opportunities

E Arrieta-Bolaños, DC Oliveira… - Bone Marrow …, 2020 - nature.com
Hematopoietic cell transplantation (HCT) is in many cases the only curative approach to
treat patients with hematologic malignant diseases. In addition, it is used to treat …

[HTML][HTML] Identification of human leukocyte antigen in precancerous and cancerous cervical lesions from Ecuadorian women

MJ Mora, R de los Ángeles Bayas-Rea, L Mejía… - Infection, Genetics and …, 2022 - Elsevier
Cervical cancer is the fourth most common type of cancer in women. Worldwide, it is a public
health problem with around 604,127 women diagnosed per year and 341,831 deaths …

Risk HLA alleles in South America and potential new epitopes for SARS-CoV2

SS Hinojosa, V Romero - Human immunology, 2021 - Elsevier
HLA alleles are associated with the body's response to infection and the regulation of the
immune system. HLA alleles have been reported to be involved in response to viral …