Covering: 1992 up to 2023 Since their discovery, lasso peptides went from peculiarities to
be recognized as a major family of ribosomally synthesized and post-translationally modified …

Lasso peptides belong to the natural product superfamily of ribosomally synthesized and
post‐translationally modified peptides (RiPPs). They are defined by an N‐terminal …

Trapped ion mobility spectrometry (TIMS) when coupled with mass spectrometry (MS) offers
great advantages for the separation of isobaric, isomeric, and/or conformeric species. In the …

The discovery and development of novel constrained peptides that combine the advantages
of therapeutic proteins with those of small molecules has partially prompted the re …

The bacteriocin microcin J25 (MccJ25) inhibits the growth of Gram-negative pathogens
including Salmonella and Shigella species, and Escherichia coli. This 21-amino acid …

Using genome mining and heterologous expression, we report the discovery and production
of a new antimicrobial lasso peptide from species related to the Enterobacter cloacae …

To make the vast collections of well-documented human clinical samples archived in
biobanks accessible for mass spectrometry imaging (MSI), recent developments have …

A fast quantum-mechanical approach, density-functional tight-binding combined with the
fragment molecular orbital method and periodic boundary conditions, is used to optimize …

The advances of genomic sequence analyses and genome mining tools have enabled the
exploration of untapped microbial natural products. Through genome mining studies to …

Lasso peptides are ribosomally synthesized and post-translationally modified peptides
produced by bacteria. They are characterized by an unusual lariat-knot structure. Targeted …