Associations of MTHFR Gene Polymorphisms with Hypertension and Hypertension in Pregnancy: A Meta-Analysis from 114 Studies with 15411 Cases and 21970 …

B Yang, S Fan, X Zhi, Y Li, Y Liu, D Wang, M He… - PloS one, 2014 - journals.plos.org
Background Several epidemiological studies have investigated the associations of
methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms with …

Association between methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms and essential hypertension: a systematic review and meta …

YL Wu, CY Hu, SS Lu, FF Gong, F Feng, ZZ Qian… - Metabolism, 2014 - Elsevier
Objective Many studies have investigated the role of 5, 10-methylenetetrahydrofolate
reductase gene (MTHFR) C677T/A1298C polymorphisms in essential hypertension (EH) …

Evidence on the causal link between homocysteine and hypertension from a meta‐analysis of 40 173 individuals implementing Mendelian randomization

L Fu, Y Li, D Luo, S Deng, B Wu… - The Journal of Clinical …, 2019 - Wiley Online Library
Numerous researchers have investigated the associations among
methylenetetrahydrofolate reductase gene (MTHFR) C677T polymorphism, homocysteine …

Association Between MTHFR Polymorphisms and the Risk of Essential Hypertension: An Updated Meta-analysis

H Meng, S Huang, Y Yang, X He, L Fei, Y Xing - Frontiers in genetics, 2021 - frontiersin.org
Background: Since the 1990s, there have been a lot of research on single-nucleotide
polymorphism (SNP) and different diseases, including many studies on 5, 10 …

Methylenetetrahydrofolate reductase polymorphism (rs1801133) and the risk of hypertension among african populations: A narrative synthesis of literature

SE Mabhida, B Muhamed, JR Sharma, T Apalata… - Genes, 2022 - mdpi.com
In this review, we have gathered and analyzed the available genetic evidence on the
association between the methylenetetrahydrofolate reductase gene (MTHFR), rs1801133 …

Riboflavin status, MTHFR genotype and blood pressure: current evidence and implications for personalised nutrition

E McAuley, H McNulty, C Hughes, JJ Strain… - Proceedings of the …, 2016 - cambridge.org
Clinical deficiency of the B-vitamin riboflavin (vitamin B2) is largely confined to developing
countries; however accumulating evidence indicates that suboptimal riboflavin status is a …

Effect of interaction between occupational stress and polymorphisms of MTHFR gene and SELE gene on hypertension

F Yang, R Qiu, S Abudoubari, N Tao, H An - PeerJ, 2022 - peerj.com
Background Gene-environment interaction is related to the prevalence of hypertension, but
the impact of genetic polymorphisms on hypertension may vary due to different geography …

Association of methylenetetrahydrofolate reductase gene (C677T) with the risk of hypertension in Morocco

S Nassereddine, Y Kassogue, F Korchi, R Habbal… - BMC research …, 2015 - Springer
Background Hypertension is a multifactorial disease caused by the interaction between
genetic and environmental factors. Mutations in the methylenetetrahydrofolate reductase …

The association of MTHFR (rs1801133) with hypertension in an indigenous south African population

SE Mabhida, JR Sharma, T Apalata, C Masilela… - Frontiers in …, 2022 - frontiersin.org
Aims: The current study sought to investigate the association between the
methylenetetrahydrofolate reductase (MTHFR) variant (rs1801133) and the risk of …

Methylenetetrahydrofolate reductase gene Rs1801133 and Rs1801131 polymorphisms and essential hypertension risk: a comprehensive analysis

Y Fan, L Wu, W Zhuang - Cardiovascular Therapeutics, 2022 - Wiley Online Library
Background. Essential hypertension (EH) is a common and multifactorial disorder that is
likely to be influenced by multiple genes. The methylenetetrahydrofolate reductase (MTHFR) …