The role of innate and adaptive immune cells in skeletal muscle regeneration
Skeletal muscle regeneration is highly dependent on the inflammatory response. A wide
variety of innate and adaptive immune cells orchestrate the complex process of muscle …
variety of innate and adaptive immune cells orchestrate the complex process of muscle …
Cell therapy to improve regeneration of skeletal muscle injuries
Diseases that jeopardize the musculoskeletal system and cause chronic impairment are
prevalent throughout the Western world. In Germany alone,~ 1.8 million patients suffer from …
prevalent throughout the Western world. In Germany alone,~ 1.8 million patients suffer from …
Time course of immune response and immunomodulation during normal and delayed healing of musculoskeletal wounds
Single trauma injuries or isolated fractures are often manageable and generally heal without
complications. In contrast, high-energy trauma results in multi/poly-trauma injury patterns …
complications. In contrast, high-energy trauma results in multi/poly-trauma injury patterns …
Multiscale analysis of a regenerative therapy for treatment of volumetric muscle loss injury
Skeletal muscle possesses a remarkable capacity to regenerate when injured, but when
confronted with major traumatic injury resulting in volumetric muscle loss (VML), the …
confronted with major traumatic injury resulting in volumetric muscle loss (VML), the …
[HTML][HTML] Advances in biomaterials for skeletal muscle engineering and obstacles still to overcome
MM Smoak, AG Mikos - Materials today bio, 2020 - Elsevier
Repair of injured skeletal muscle is a sophisticated process that uses immune, muscle,
perivascular, and neural cells. In acute injury, the robust endogenous repair process can …
perivascular, and neural cells. In acute injury, the robust endogenous repair process can …
Biomaterial and stem cell‐based strategies for skeletal muscle regeneration
Adult skeletal muscle can regenerate effectively after mild physical or chemical insult.
Muscle trauma or disease can overwhelm this innate capacity for regeneration and result in …
Muscle trauma or disease can overwhelm this innate capacity for regeneration and result in …
Musculoskeletal regeneration, rehabilitation, and plasticity following traumatic injury
The musculoskeletal system has an integral role throughout life, including structural support
to the body, protection, and allowing a range of fine to complex movements for daily living to …
to the body, protection, and allowing a range of fine to complex movements for daily living to …
Laminin-111-Enriched fibrin hydrogels enhance functional muscle regeneration following trauma
Volumetric muscle loss (VML) is the surgical or traumatic loss of skeletal muscle, which can
cause loss of limb function or permanent disability. VML injuries overwhelms the …
cause loss of limb function or permanent disability. VML injuries overwhelms the …
Inflammatory and physiological consequences of debridement of fibrous tissue after volumetric muscle loss injury
BT Corona, JC Rivera… - Clinical and translational …, 2018 - Wiley Online Library
Volumetric muscle loss (VML) injuries present chronic loss of muscle fibers followed by
expansive fibrotic tissue deposition. Regenerative medicine therapies are under …
expansive fibrotic tissue deposition. Regenerative medicine therapies are under …
RAGE signaling in skeletal biology
LI Plotkin, AL Essex, HM Davis - Current osteoporosis reports, 2019 - Springer
Abstract Purpose of Review The receptor for advanced glycation end products (RAGE) and
several of its ligands have been implicated in the onset and progression of pathologies …
several of its ligands have been implicated in the onset and progression of pathologies …