Enzyme-based chemical biosensors are based on biological recognition. In order to
operate, the enzymes must be available to catalyze a specific biochemical reaction and be …

The restricted view of tumour progression as a multistep process defined by the
accumulation of mutations in cancer cells has largely ignored the substantial contribution of …

Simple Summary CD3-bispecific antibody therapy is a form of immunotherapy that enables
soldier cells of the immune system to recognize and kill tumor cells. This type of therapy is …

The tumor microenvironment (TME) of head and neck squamous cell carcinoma (HNSCC) is
comprised of cancer-associated fibroblasts (CAFs), immune cells, and other supporting …

Purpose The role of the microenvironment during the initiation and progression of
carcinogenesis is now realized to be of critical importance, both for enhanced understanding …

An outstanding characteristic of gliomas is their infiltration into brain parenchyma, a property
that impairs complete surgical resection; consequently, these tumors might recur, resulting in …

Stimulus‐responsive fluorescence imaging modality shows great promise for detection of
tumor due to the advantages of high sensitivity, simplicity and noninvasiveness. However …

Proteases play critical roles in virtually all biological processes, including proliferation, cell
death and survival, protein turnover, and migration. However, when dysregulated, these …

Proteolytic enzymes may serve as promising targets for novel therapeutic treatment
strategies seeking to impede cancer progression and metastasis. One such enzyme is …

Matrix metalloproteinases (MMPs) are identifiable members of proteolytic enzymes that can
degrade a wide range of proteins in the extracellular matrix (ECM). MMPs can be …