Malaria is caused by the protozoan Plasmodium, transmitted to humans by Anopheles
mosquitoes. The most dangerous of the plasmodia infecting humans is Plasmodium …

Review underscores the ubiquitous contribution of IFN-δ to immune responses against
malaria, evidence for its protective role and critical issues relating to its induction. Immune …

Pro-and antiinflammatory cytokines were measured on admission in 287 consecutive
Vietnamese adults with severe falciparum malaria. Plasma interleukin (IL)-6, IL-10, and …

Background Severe anaemia is a major complication of malaria but little is known about its
pathogenesis. Experimental models have implicated tumour necrosis factor (TNF) in …

ABSTRACT We compared interleukin-12 (IL-12) and other cytokine activities during and
after an acute clinical episode in a matched-pair case-control study of young African children …

Systemic release of tumor necrosis factor (TNF) and lymphotoxin-α (LTα) has been found to
contribute to the severity of non-Hodgkin's lymphoma (NHL). We investigated whether …

The contribution of T cell-mediated responses was studied with regard to resistance to
reinfection in groups of Gabonese children participating in a prospective study of severe and …

TNF signals through two distinct receptors, designated TNFR1 and TNFR2, which initiate
diverse cellular effects that include cell survival, activation, differentiation, and proliferation …

Background Routine antipyretic therapy in children with infectious diseases has long been
the source of controversy. Each year, in addition to antimalarial medication, millions of …

Abstract Interleukin (IL)—12 and transforming growth factor (TGF)—β 1 regulate the balance
between pro-and anti-inflammatory cytokines in animal models of malaria. Since the …