Pseudomonas aeruginosa causes severe and persistent infections in immune compromised
individuals and cystic fibrosis sufferers. The infection is hard to eradicate as P. aeruginosa …

The Pseudomonas quinolone signal (PQS) has been studied primarily in the context of its
role as a quorum-sensing signaling molecule. Recent data suggest, however, that this …

Bacteria become highly tolerant to antibiotics when nutrients are limited. The inactivity of
antibiotic targets caused by starvation-induced growth arrest is thought to be a key …

Xanthomonas oryzae pv. oryzae (Xoo) is widely prevalent and causes Bacterial Leaf Blight
(BLB) in Basmati rice grown in different areas of Pakistan. There is a need to use …

Since quinine was first isolated, animals, plants and microorganisms producing a wide
variety of quinolone compounds have been discovered, several of which possess …

Covering: July 2005 to June 2006. Previous review: Nat. Prod. Rep., 2007, 24, 223–246 This
review covers the isolation, structure determination, synthesis and biological activity of …

Bacteria communicate through the production of diffusible signal molecules termed
autoinducers. The molecules are produced at basal levels and accumulate during growth …

Many bacteria use extracellular signals to communicate and coordinate social activities, a
process referred to as quorum sensing. Many quorum signals have significant hydrophobic …

The sputum (mucus) layer of the cystic fibrosis (CF) lung is a complex substrate that provides
Pseudomonas aeruginosa with carbon and energy to support high-density growth during …

Chronic coinfections of Staphylococcus aureus and Pseudomonas aeruginosa frequently
fail to respond to antibiotic treatment, leading to significant patient morbidity and mortality …