Molecular biology of Burkitt's lymphoma

JL Hecht, JC Aster - Journal of clinical oncology, 2000 - ascopubs.org
The diagnostic category of Burkitt's lymphoma encompasses a closely related group of
aggressive B-cell tumors that includes sporadic, endemic, and human immunodeficiency …

B cell chronic lymphocytic leukemia: lessons learned from studies of the B cell antigen receptor

N Chiorazzi, M Ferrarini - Annual review of immunology, 2003 - annualreviews.org
B cell chronic lymphocytic leukemia (B-CLL) is an accumulative disease of slowly
proliferating CD5+ B lymphocytes that develops in the aging population. Whereas some …

Clinical impact of the differentiation profile assessed by immunophenotyping in patients with diffuse large B-cell lymphoma

L Colomo, A López-Guillermo… - Blood, The Journal …, 2003 - ashpublications.org
To analyze the relationship between immunophenotyping profile and main
clinicopathological features and outcome in diffuse large B-cell lymphoma (DLBCL), we …

Whole-genome sequencing reveals activation-induced cytidine deaminase signatures during indolent chronic lymphocytic leukaemia evolution

S Kasar, J Kim, R Improgo, G Tiao, P Polak… - Nature …, 2015 - nature.com
Patients with chromosome 13q deletion or normal cytogenetics represent the majority of
chronic lymphocytic leukaemia (CLL) cases, yet have relatively few driver mutations. To …

Deregulated BCL6 expression recapitulates the pathogenesis of human diffuse large B cell lymphomas in mice

G Cattoretti, L Pasqualucci, G Ballon, W Tam… - Cancer cell, 2005 - cell.com
Diffuse large B cell lymphomas (DLBCL) derive from germinal center (GC) B cells and
display chromosomal alterations deregulating the expression of BCL6, a transcriptional …

Mutations of the BCL6 proto-oncogene disrupt its negative autoregulation in diffuse large B-cell lymphoma

L Pasqualucci, A Migliazza, K Basso… - Blood, The Journal …, 2003 - ashpublications.org
The BCL6 proto-oncogene encodes a transcriptional repressor whose expression is
deregulated by chromosomal translocations in approximately 40% of diffuse large B-cell …

The molecular pathogenesis of primary mediastinal large B-cell lymphoma

C Steidl, RD Gascoyne - Blood, The Journal of the American …, 2011 - ashpublications.org
Primary mediastinal large B-cell lymphoma (PMBCL) is a recognized non-Hodgkin
lymphoma entity with unique pathologic, clinical, and molecular characteristics distinct from …

Clinical significance of CD38 expression in chronic lymphocytic leukemia

G Del Poeta, L Maurillo, A Venditti… - Blood, The Journal …, 2001 - ashpublications.org
B-cell chronic lymphocytic leukemia (B-CLL) follows heterogeneous clinical courses, and
several biological parameters need to be added to the current clinical staging systems to …

Prognostic biomarkers in diffuse large B-cell lymphoma

IS Lossos, D Morgensztern - Journal of clinical oncology, 2006 - ascopubs.org
Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin's
lymphoma. Although it represents a curable disease, less than half of the patients are cured …

Distinctive patterns of BCL6 molecular alterations and their functional consequences in different subgroups of diffuse large B-cell lymphoma

J Iqbal, TC Greiner, K Patel, BJ Dave, L Smith, J Ji… - Leukemia, 2007 - nature.com
Gene expression profiling of diffuse large B-cell lymphoma (DLBCL) has revealed
biologically and prognostically distinct subgroups: germinal center B-cell-like (GCB) …