New insights into roles of acidocalcisomes and contractile vacuole complex in osmoregulation in protists

R Docampo, V Jimenez, N Lander, ZH Li… - International review of cell …, 2013 - Elsevier
While free-living protists are usually subjected to hyposmotic environments, parasitic protists
are also in contact with hyperosmotic habitats. Recent work in one of these parasites …

The acidocalcisome as a target for chemotherapeutic agents in protozoan parasites

R Docampo, SNJ Moreno - Current pharmaceutical design, 2008 - ingentaconnect.com
Acidocalcisomes are acidic organelles rich in calcium and phosphorus that have been
conserved from bacteria to man. In parasitic protozoa acidocalcisomes possess enzymes …

Ultrastructural characterization of melanosomes of the human pathogenic fungus Fonsecaea pedrosoi

AJ Franzen, MML Cunha, K Miranda… - Journal of structural …, 2008 - Elsevier
Melanin is a complex polymer widely distributed in nature and has been described as an
important virulence factor in pathogenic fungi. In the majority of fungi, the mechanism of …

Type IH+-pyrophosphatase regulates the vacuolar storage of sucrose in citrus fruit

SB Hussain, CY Shi, LX Guo, W Du… - Journal of …, 2020 - academic.oup.com
The aim of this work was to evaluate the general role of the vacuolar pyrophosphatase
proton pump (V-PPase) in sucrose accumulation in citrus species. First, three citrus V-PPase …

Proton-pyrophosphatase and polyphosphate in acidocalcisome-like vesicles from oocytes and eggs of Periplaneta americana

LS Motta, IB Ramos, FM Gomes, W de Souza… - Insect biochemistry and …, 2009 - Elsevier
Acidocalcisomes are acidic organelles containing large amounts of polyphosphate (poly P),
a number of cations, and a variety of cation pumps in their limiting membrane. The vacuolar …

Volutin granules of Eimeria parasites are acidic compartments and have physiological and structural characteristics similar to acidocalcisomes

LC Soares Medeiros, F Gomes… - Journal of Eukaryotic …, 2011 - Wiley Online Library
The structural organization of parasites has been the subject of investigation by many
groups and has lead to the identification of structures and metabolic pathways that may …

Role of H+-pyrophosphatase activity in the regulation of intracellular pH in a scuticociliate parasite of turbot: Physiological effects

N Mallo, J Lamas, AP de Felipe, RA Sueiro… - Experimental …, 2016 - Elsevier
The scuticociliatosis is a very serious disease that affects the cultured turbot, and whose
causal agent is the anphizoic and marine euryhaline ciliate Philasterides dicentrarchi …

CrATP as a new inhibitor of ecto-ATPases of trypanosomatids

OC Moreira, PF Rios, FF Esteves… - Parasitology, 2009 - cambridge.org
Trypanosomatid protozoa include heteroxenic species some of them pathogenic for men,
animals and plants. Parasite membrane contains ecto-enzymes whose active sites face the …

Kinetics of pyrophosphate-driven proton uptake by acidocalcisomes of Leptomonas wallacei

BLM Moreira, LCAS Medeiros, K Miranda… - Biochemical and …, 2005 - Elsevier
In this work, we show the kinetics of pyrophosphate-driven H+ uptake by acidocalcisomes in
digitonin-permeabilized promastigotes of Leptomonas wallacei. The vacuolar proton …

Characterization of Ca2+ uptake in a subcellular membrane fraction of Herpetomonas sp. promastigotes

CL Sodré, BLM Moreira, JR Meyer-Fernandes… - Parasitology, 2009 - cambridge.org
ATP-dependent Ca2+ uptake was studied in a subcellular fraction from Herpetomonas sp.
prepared by mechanical disruption and using 45Ca2+ as a tracer. The uptake was …