Age-related mitochondrial dysfunction as a key factor in COVID-19 disease

DJM Fernández-Ayala, P Navas… - Experimental gerontology, 2020 - Elsevier
SARS-CoV-2 causes a severe pneumonia (COVID-19) that affects essentially elderly
people. In COVID-19, macrophage infiltration into the lung causes a rapid and intense …

Mechanisms contributing to adverse outcomes of COVID-19 in obesity

M Sudhakar, SB Winfred, G Meiyazhagan… - Molecular and cellular …, 2022 - Springer
A growing amount of epidemiological data from multiple countries indicate an increased
prevalence of obesity, more importantly central obesity, among hospitalized subjects with …

COVID-19 autopsy cases: detection of virus in endocrine tissues

AM Poma, D Bonuccelli, R Giannini, E Macerola… - Journal of …, 2022 - Springer
Abstract Purpose The SARS-CoV-2 genome has been detected in a variety of human
samples including blood, urine, semen, and faeces. However, evidence of virus presence in …

Can selective serotonin reuptake inhibitors have a neuroprotective effect during COVID-19?

LHA Costa, BM Santos, LGS Branco - European journal of pharmacology, 2020 - Elsevier
The absence of a specific treatment for SARS-CoV-2 infection led to an intense global effort
in order to find new therapeutic interventions and improve patient outcomes. One important …

Obesity Is associated with an impaired baseline repertoire of anti-influenza virus antibodies

M Abd Alhadi, LM Friedman, EA Karlsson… - Microbiology …, 2023 - Am Soc Microbiol
Obesity is a risk factor for severe disease and mortality for both influenza and severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. While previous studies show …

Neurological manifestations of COVID-19 in patients: from path physiology to therapy

JJ Merino, A Macho-González, J Benedi… - Neurological …, 2021 - Springer
Coronavirus is a family of ARN positive single-stranded belonging to the family of
Coronaviridae. There are several families of coronavirus that transmit more or less serious …

Functional and tissue enrichment analyses suggest that SARS-CoV-2 infection affects host metabolism and catabolism mediated by interference on host proteins

LR Lopes - Brazilian Journal of Microbiology, 2021 - Springer
Abstract Infection by SARS-CoV-2, the causative agent of COVID-19, is critically connected
with host metabolism. Through functional enrichment analysis, the present study aims to …