The study of experimental colon carcinogenesis in rodents has a long history, dating back
almost 80 years. There are many advantages to studying the pathogenesis of carcinogen …

Diquat (1, 1′-ethylene-2, 2′-bipyridinium ion; DQ) is a nonselective quick-acting
herbicide, which is used as contact and preharvest desiccant to control terrestrial and …

To develop an efficient animal model for colitis‐related carcinogenesis, male Crj: CD‐1
(ICR) mice were given a single intraperitoneal administration (10 mg/kg body weight) of a …

Activation of colonic proteinase-activated receptor-2 (PAR-2) provokes colonic inflammation
and increases mucosal permeability in mice. The mechanism of inflammation is under …

The development of an individual during fetal life and childhood is characterized by rapid
growth as well as gradual maturation of organs and systems. Beyond the nutritional intake in …

Oxidative stress plays a crucial role in the manifestations of maneb (MB) and paraquat (PQ)-
induced toxicity including MB+ PQ-induced Parkinson's disease (PD). Polymorphonuclear …

Nitrates have long been considered as harmful dietary components and judged responsible
for deleterious effects on human health, leading to stringent regulations concerning their …

To better understand the biochemical consequences when polymeric polyphenols serve as
biological antioxidants, we studied how reaction pH (pH 2.1–7.4) and protein affected the …

Capsaicin-sensitive afferent nerves are described as being protective against gastric
inflammation; their destruction leads to an exacerbation of inflammatory processes …

Diquat (DQ) is among the most widely used herbicides, and its intake can cause severe
systemic toxicity that manifests rapidly. The resultant symptoms can cause the dysfunction of …