Recent proteomic analyses of snake venoms show that metalloproteinases represent major
components in most of the Crotalid and Viperid venoms. In this chapter we discuss the …

The covalent binding of complement components C3 and C4 is critical for their activities.
This reaction is made possible by the presence of an internal thioester in the native protein …

Subtilosin A, a new antibiotic produced by Bacillus subtilis 168, was extracted from culture
medium with n-butanol and purified to homogeneity by a combination of gel filtration and …

These studies explore the role of conformational change and exposed carbohydrate
residues in the clearance of alpha 2-macroglobulin-trypsin (alpha 2M-T) complexes in the …

The primary structure of the tetrameric plasma glycoprotein human alpha 2-macroglobulin
has been determined. The identical subunits contain 1451 amino acid residues …

Pulmonary surfactant contains two hydrophobic polypeptides, SP-B and SP-C, with known
amino acid sequences and with truncated subforms lacking the N-terminal residues …

A comparison of the sequence of the subunit of human alpha 2-macroglobulin (alpha 2M;
1451 amino acid residues) with that of murine complement component pro-C3 (1639 amino …

Thioester-containing proteins (TEPs) are conserved proteins among insects that are thought
to be involved in innate immunity. In Drosophila, the Tep family is composed of 6 genes …

The fibrinolytic system comprises a proenzyme, plasminogen, which can be activated to the
active enzyme plasmin, that will degrade fibrin by different types of plasminogen activators …

Native human pregnancy zone protein (PZP), a close homolog of alpha 2-macroglobulin
(alpha 2M), can be obtained in approximately 20% yield from pooled late pregnancy plasma …