Design of Experiments and machine learning for product innovation: A systematic literature review

R Arboretti, R Ceccato, L Pegoraro… - Quality and Reliability …, 2022 - Wiley Online Library
The recent increase in digitalization of industrial systems has resulted in a boost in data
availability in the industrial environment. This has favored the adoption of machine learning …

Lipid-based nanocarriers for ophthalmic administration: towards experimental design implementation

FM González-Fernández, A Bianchera, P Gasco… - Pharmaceutics, 2021 - mdpi.com
Nanotherapeutics based on biocompatible lipid matrices allow for enhanced solubility of
poorly soluble compounds in the treatment of ophthalmic diseases, overcoming the …

Microfluidic manufacturing of liposomes: development and optimization by design of experiment and machine learning

R Rebollo, F Oyoun, Y Corvis… - … Applied Materials & …, 2022 - ACS Publications
Liposomes constitute the most exploited drug-nanocarrier with several liposomal drugs on
the market. Microfluidic-based preparation methods stand up as a promising approach with …

Machine learning in chemical product engineering: The state of the art and a guide for newcomers

C Trinh, D Meimaroglou, S Hoppe - Processes, 2021 - mdpi.com
Chemical Product Engineering (CPE) is marked by numerous challenges, such as the
complexity of the properties–structure–ingredients–process relationship of the different …

Integrated design of emulsified cosmetic products: A review

F Calvo, JM Gómez, L Ricardez-Sandoval… - … Research and Design, 2020 - Elsevier
Chemical product design has progressively become a more critical issue since the chemical
industry is rapidly moving toward the production of consumer-oriented products at low cost …

Lipid nanoparticles as carriers of cyclodextrin inclusion complexes: A promising approach for cutaneous delivery of a volatile essential oil

FQ Pires, JKR da Silva, LL Sa-Barreto, T Gratieri… - Colloids and Surfaces B …, 2019 - Elsevier
Solid inclusion complexes with cyclodextrins (CD) may be used to overcome volatility and
solubility problems of essential oils of pharmacological interest. However, they lack the …

New tools to design smart thermosensitive hydrogels for protein rectal delivery in IBD

L Garcia-del Rio, P Diaz-Rodriguez… - Materials Science and …, 2020 - Elsevier
Abstract Local treatment of Inflammatory Bowel Disease (IBD) has been pointed out to be a
novel therapeutic approach with several advantages when compared to conventional …

The impact of the integrated development of AI and energy industry on regional energy industry: A case of china

F Dong, S Zhang, J Zhu, J Sun - International journal of environmental …, 2021 - mdpi.com
With the advent of the Energy 4.0 era, the adoption of “Internet+ artificial intelligence”
systems will enable the transformation and upgrading of the traditional energy industry. This …

Streamlined plug-in aerosol prototype for reconfigurable manufacture of nano-drug delivery systems

S Maharjan, M Gautam, K Poudel, CS Yong, SK Ku… - Biomaterials, 2022 - Elsevier
The significant advances in nano-drug delivery systems (NDDS) for anticancer agents have
led to the development of computational techniques, such as machine learning and neural …

Tailor-made oligonucleotide-loaded lipid-polymer nanosystems designed for bone gene therapy

P Garcia-Garcia, E Briffault, M Landin, C Evora… - Drug delivery and …, 2021 - Springer
Gene therapy has emerged as a tool for the treatment of systemic metabolic disorders as
osteoporosis (OP). However, the design of a suitable vehicle able to efficiently load and …