Aging is characterized by a progressive deterioration of physiological integrity, leading to
impaired functional ability and ultimately increased susceptibility to death. It is a major risk …

Sex differences in stress responses can be found at all stages of life and are related to both
the organizational and activational effects of gonadal hormones and to genes on the sex …

Alzheimer's disease has a higher incidence in older women, with a spike in cognitive
decline that tracks with visceral adiposity, dysregulated energy homeostasis and bone loss …

The study aims to discuss the effects of aging on the male reproductive system. A systematic
review was performed using PubMed from 1980 to 2014. Aging is a natural process …

Follicle-stimulating hormone (FSH) is involved in mammalian reproduction via binding to
FSH receptor (FSHR). However, several studies have found that FSH and FSHR play …

ABSTRACT Introduction Testosterone (T) deficiency (TD) may significantly affect sexual
function and multiple organ systems. Aim To provide recommendations and Standard …

Hormones of the hypothalamic-pituitary-gonadal (HPG) axis that regulate reproductive
function have multiple effects on the development, maintenance and function of the brain …

It is well recognized that bone loss accelerates in hypogonadal states, with female
menopause being the classic example of sex hormones affecting the regulation of bone …

Sex differences in lifespan exist world-wide, with women outliving men by more than a
decade in some countries. The gender gap is not a uniquely human phenomenon; most …

Parenthood at an older age is becoming a trend among men, especially in the most
developed societies. Aging has a significant impact on male fertility. Older men exhibit …