Cycles in epilepsy

PJ Karoly, VR Rao, NM Gregg, GA Worrell… - Nature Reviews …, 2021 - nature.com
Epilepsy is among the most dynamic disorders in neurology. A canonical view holds that
seizures, the characteristic sign of epilepsy, occur at random, but, for centuries, humans …

High‐frequency oscillations: the state of clinical research

B Frauscher, F Bartolomei, K Kobayashi… - …, 2017 - Wiley Online Library
Modern electroencephalographic (EEG) technology contributed to the appreciation that the
EEG signal outside the classical Berger frequency band contains important information. In …

Noninvasive high-frequency oscillations riding spikes delineates epileptogenic sources

Z Cai, A Sohrabpour, H Jiang, S Ye… - Proceedings of the …, 2021 - National Acad Sciences
High-frequency oscillations (HFOs) are a promising biomarker for localizing epileptogenic
brain and guiding successful neurosurgery. However, the utility and translation of …

HFO to measure seizure propensity and improve prognostication in patients with epilepsy

J Jacobs, M Zijlmans - Epilepsy Currents, 2020 - journals.sagepub.com
The study of high frequency oscillations (HFO) in the electroencephalogram (EEG) as
biomarkers of epileptic activity has merely focused on their spatial location and relationship …

Graph measures of node strength for characterizing preictal synchrony in partial epilepsy

S Courtens, B Colombet, A Trébuchon, A Brovelli… - Brain …, 2016 - liebertpub.com
The reference electrophysiological pattern at seizure onset is the “rapid discharge,” as
visible on intracerebral electroencephalography (EEG). This discharge typically corresponds …

[HTML][HTML] Sleep influences the intracerebral EEG pattern of focal cortical dysplasia

IM Cordeiro, N Von Ellenrieder, N Zazubovits… - Epilepsy research, 2015 - Elsevier
Objective Focal cortical dysplasia (FCD) is able to generate an intrinsic pathological EEG
activity characterized by a continuous or near-continuous spiking. Different patterns of …

Spatiotemporal changes in regularity of gamma oscillations contribute to focal ictogenesis

Y Sato, SM Wong, Y Iimura, A Ochi, SM Doesburg… - Scientific reports, 2017 - nature.com
In focal ictogenesis, gamma oscillations (30–70 Hz) recorded by electroencephalography
(EEG) are related to the epileptiform synchronization of interneurons that links the seizure …

Effects of focal brain cooling on extracellular concentrations of neurotransmitters in patients with epilepsy

S Nomura, T Inoue, H Imoto, E Suehiro, Y Maruta… - …, 2017 - Wiley Online Library
Objective Brain hypothermia controls epileptic discharge and reduces extracellular
concentrations of glutamate (Glu), an excitatory neurotransmitter. We aimed to determine the …

Preictal variability of high‐frequency oscillation rates in refractory epilepsy

JM Scott, S Ren, SV Gliske, WC Stacey - Epilepsia, 2020 - Wiley Online Library
Abstract Objective High‐frequency oscillations (HFOs) have shown promising utility in the
spatial localization of the seizure onset zone for patients with focal refractory epilepsy …

[HTML][HTML] Widespread slow oscillations support interictal epileptiform discharge networks in focal epilepsy

H Ye, L Ye, L Hu, Y Yang, Y Ge, R Chen, S Wang… - Neurobiology of …, 2024 - Elsevier
Interictal epileptiform discharges (IEDs) often co-occur across spatially-separated cortical
regions, forming IED networks. However, the factors prompting IED propagation remain …