[HTML][HTML] Emerging pollutants in the EU: 10 years of NORMAN in support of environmental policies and regulations

V Dulio, B van Bavel, E Brorström-Lundén… - Environmental Sciences …, 2018 - Springer
Abstract In 2005, the European Commission funded the NORMAN project to promote a
permanent network of reference laboratories and research centers, including academia …

[HTML][HTML] In vitro or not in vitro: a short journey through a long history

K Rehberger, C Kropf, H Segner - Environmental Sciences Europe, 2018 - Springer
The aim of ecotoxicology is to study toxic effects on constituents of ecosystems, with the
protection goal being populations and communities rather than individual organisms. In this …

Towards the review of the European Union Water Framework Directive: recommendations for more efficient assessment and management of chemical contamination …

W Brack, V Dulio, M Ågerstrand, I Allan… - Science of the Total …, 2017 - Elsevier
Water is a vital resource for natural ecosystems and human life, and assuring a high quality
of water and protecting it from chemical contamination is a major societal goal in the …

Effect-based trigger values for in vitro and in vivo bioassays performed on surface water extracts supporting the environmental quality standards (EQS) of the …

BI Escher, S Aїt-Aїssa, PA Behnisch, W Brack… - Science of the Total …, 2018 - Elsevier
Abstract Effect-based methods including cell-based bioassays, reporter gene assays and
whole-organism assays have been applied for decades in water quality monitoring and …

Regulatory risk assessment of pharmaceuticals in the environment: Current practice and future priorities

R Oldenkamp, T Hamers, J Wilkinson… - Environmental …, 2024 - Wiley Online Library
How can data on the occurrence of pharmaceuticals and personal care products (PPCPs) in
the environment and the quality of ecosystems exposed to PPCPs be used to determine …

[HTML][HTML] Biological effect and chemical monitoring of Watch List substances in European surface waters: steroidal estrogens and diclofenac–effect-based methods for …

E Simon, A Duffek, C Stahl, M Frey, M Scheurer… - Environment …, 2022 - Elsevier
rationale of the study Three steroidal estrogens, 17α-ethinylestradiol (EE2), 17β-estradiol
(E2), estrone (E1), and the non-steroidal anti-inflammatory drug (NSAID), diclofenac have …

Bioassay battery interlaboratory investigation of emerging contaminants in spiked water extracts–towards the implementation of bioanalytical monitoring tools in water …

C Di Paolo, R Ottermanns, S Keiter, S Ait-Aissa… - Water research, 2016 - Elsevier
Bioassays are particularly useful tools to link the chemical and ecological assessments in
water quality monitoring. Different methods cover a broad range of toxicity mechanisms in …

[HTML][HTML] Toxicity assessment of total petroleum hydrocarbons in aquatic environments using the bioluminescent bacterium Aliivibrio fischeri

M Mirjani, M Soleimani, V Salari - Ecotoxicology and environmental safety, 2021 - Elsevier
Toxicity monitoring of environmental pollutants especially petroleum hydrocarbons as
priority pollutants is an important environmental issue. This study addresses a rapid …

Risk‐based approach in the revised European Union drinking water legislation: Opportunities for bioanalytical tools

MML Dingemans, KA Baken… - Integrated …, 2019 - Wiley Online Library
ABSTRACT A plethora of in vitro bioassays are developed in the context of chemical risk
assessment and clinical diagnostics to test effects on different biological processes. Such …

Validation of Arxula Yeast Estrogen Screen assay for detection of estrogenic activity in water samples: results of an international interlaboratory study

K Hettwer, M Jähne, K Frost, M Giersberg… - Science of the Total …, 2018 - Elsevier
Endocrine-active substances can adversely impact the aquatic ecosystems. A special
emphasis is laid, among others, on the effects of estrogens and estrogen mimicking …