Neurofibromatosis type 2 (NF2) and the implications for vestibular schwannoma and meningioma pathogenesis
Patients diagnosed with neurofibromatosis type 2 (NF2) are extremely likely to develop
meningiomas, in addition to vestibular schwannomas. Meningiomas are a common primary …
meningiomas, in addition to vestibular schwannomas. Meningiomas are a common primary …
Meningioma DNA methylation groups identify biological drivers and therapeutic vulnerabilities
Meningiomas are the most common primary intracranial tumors. There are no effective
medical therapies for meningioma patients, and new treatments have been encumbered by …
medical therapies for meningioma patients, and new treatments have been encumbered by …
[HTML][HTML] Meningioma genomics: diagnostic, prognostic, and therapeutic applications
There has been a recent revolution in our understanding of the genetic factors that drive
meningioma, punctuating an equilibrium that has existed since Cushing's germinal studies …
meningioma, punctuating an equilibrium that has existed since Cushing's germinal studies …
Genomic landscape of high-grade meningiomas
High-grade meningiomas frequently recur and are associated with high rates of morbidity
and mortality. To determine the factors that promote the development and evolution of these …
and mortality. To determine the factors that promote the development and evolution of these …
Multiplatform genomic profiling and magnetic resonance imaging identify mechanisms underlying intratumor heterogeneity in meningioma
ST Magill, HN Vasudevan, K Seo… - Nature …, 2020 - nature.com
Meningiomas are the most common primary intracranial tumors, but the molecular drivers of
meningioma tumorigenesis are poorly understood. We hypothesized that investigating …
meningioma tumorigenesis are poorly understood. We hypothesized that investigating …
Radiographic prediction of meningioma grade by semantic and radiomic features
Objectives The clinical management of meningioma is guided by tumor grade and biological
behavior. Currently, the assessment of tumor grade follows surgical resection and …
behavior. Currently, the assessment of tumor grade follows surgical resection and …
[PDF][PDF] Comprehensive molecular profiling identifies FOXM1 as a key transcription factor for meningioma proliferation
Meningioma is the most common primary intracranial tumor, but the molecular drivers of
aggressive meningioma are incompletely understood. Using 280 human meningioma …
aggressive meningioma are incompletely understood. Using 280 human meningioma …
SMO mutation status defines a distinct and frequent molecular subgroup in olfactory groove meningiomas
Background. Meningiomas are the most common primary intracranial tumors in adults.
Identification of SMO and AKT1 mutations in meningiomas has raised the hope for targeted …
Identification of SMO and AKT1 mutations in meningiomas has raised the hope for targeted …
[HTML][HTML] Imaging brain tumour microstructure
M Nilsson, E Englund, F Szczepankiewicz… - Neuroimage, 2018 - Elsevier
Imaging is an indispensable tool for brain tumour diagnosis, surgical planning, and follow-
up. Definite diagnosis, however, often demands histopathological analysis of microscopic …
up. Definite diagnosis, however, often demands histopathological analysis of microscopic …
[HTML][HTML] Recent advances in meningioma immunogenetics
M Al-Rashed, K Foshay, M Abedalthagafi - Frontiers in Oncology, 2020 - frontiersin.org
Meningiomas are relatively common, and typically benign intracranial tumors, which in many
cases can be cured by surgical resection. However, less prevalent, high grade …
cases can be cured by surgical resection. However, less prevalent, high grade …