Treponema pallidum, the syphilis spirochete: making a living as a stealth pathogen
JD Radolf, RK Deka, A Anand, D Šmajs… - Nature Reviews …, 2016 - nature.com
The past two decades have seen a worldwide resurgence in infections caused by
Treponema pallidum subsp. pallidum, the syphilis spirochete. The well-recognized capacity …
Treponema pallidum subsp. pallidum, the syphilis spirochete. The well-recognized capacity …
Biological basis for syphilis
RE LaFond, SA Lukehart - Clinical microbiology reviews, 2006 - Am Soc Microbiol
Syphilis is a chronic sexually transmitted disease caused by Treponema pallidum subsp.
pallidum. Clinical manifestations separate the disease into stages; late stages of disease are …
pallidum. Clinical manifestations separate the disease into stages; late stages of disease are …
[HTML][HTML] Identification of vaccine targets in pathogens and design of a vaccine using computational approaches
Antigen identification is an important step in the vaccine development process.
Computational approaches including deep learning systems can play an important role in …
Computational approaches including deep learning systems can play an important role in …
[HTML][HTML] Syphilis: using modern approaches to understand an old disease
EL Ho, SA Lukehart - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Syphilis is a fascinating and perplexing infection, with protean clinical manifestations and
both diagnostic and management ambiguities. Treponema pallidum subsp. pallidum, the …
both diagnostic and management ambiguities. Treponema pallidum subsp. pallidum, the …
The endemic treponematoses
L Giacani, SA Lukehart - Clinical microbiology reviews, 2014 - Am Soc Microbiol
The agents of human treponematoses include four closely related members of the genus
Treponema: three subspecies of Treponema pallidum plus Treponema carateum. T …
Treponema: three subspecies of Treponema pallidum plus Treponema carateum. T …
The immunopathobiology of syphilis: the manifestations and course of syphilis are determined by the level of delayed-type hypersensitivity
JA Carlson, G Dabiri, B Cribier… - The American journal of …, 2011 - journals.lww.com
Syphilis has plagued mankind for centuries and is currently resurgent in the Western
hemisphere. Although there has been a significant reduction of tertiary disease and …
hemisphere. Although there has been a significant reduction of tertiary disease and …
The pathogenesis of syphilis: the Great Mimicker, revisited
RW Peeling, EW Hook III - The Journal of Pathology: A Journal …, 2006 - Wiley Online Library
Syphilis is a chronic sexually transmitted infection caused by Treponema pallidum
subspecies pallidum. Its protean clinical presentations earned it the name of the 'Great …
subspecies pallidum. Its protean clinical presentations earned it the name of the 'Great …
Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes
R Seshadri, GSA Myers, H Tettelin… - Proceedings of the …, 2004 - National Acad Sciences
We present the complete 2,843,201-bp genome sequence of Treponema denticola (ATCC
35405) an oral spirochete associated with periodontal disease. Analysis of the T. denticola …
35405) an oral spirochete associated with periodontal disease. Analysis of the T. denticola …
[HTML][HTML] The global roadmap for advancing development of vaccines against sexually transmitted infections: update and next steps
SL Gottlieb, CD Deal, B Giersing, H Rees, G Bolan… - Vaccine, 2016 - Elsevier
Abstract In 2014, the World Health Organization, the US National Institutes of Health, and
global technical partners published a comprehensive roadmap for development of new …
global technical partners published a comprehensive roadmap for development of new …
Role of Treponema denticola in periodontal diseases
MN Sela - Critical Reviews in Oral Biology & Medicine, 2001 - journals.sagepub.com
Among periodontal anaerobic pathogens, the oral spirochetes, and especially Treponema
denticola, have been associated with periodontal diseases such as early-onset periodontitis …
denticola, have been associated with periodontal diseases such as early-onset periodontitis …