The mock circulatory loop (MCL) is an in vitro experimental system that can provide
continuous pulsatile flows and simulate different physiological or pathological parameters of …

Heart failure is a major health risk, and with limited availability of donor organs, there is an
increasing need for developing cardiac assist devices (CADs). Mock circulatory loops (MCL) …

The vibration of the heart valves' closure is an important component of the heart sound and
contains important information about the mechanical activity of a heart. Stenosis of the distal …

This study aimed to evaluate a newly designed circulatory mock loop intended to model
cardiac and circulatory hemodynamics for mechanical circulatory support device testing. The …

Abstract Purpose Tetralogy of Fallot and other conditions affecting the right ventricular
outflow tract (RVOT) are common in pediatric patients, but there is a lack of quantitative …

Implantable cardiovascular devices must undergo evaluation prior to animal testing and
clinical trials to ensure their performance and efficiency. Mock circulation loops (MCLs) are …

The present study aimed to investigate the impact of pulmonary hypertension (PH) on short-
term survival after LVAD implantation with or without tricuspid annuloplasty valve repair …

Abstract Purpose Mock circulatory loops (MCLs) can reproducibly generate physiologically
relevant pressures and flows for cardiovascular device testing. These systems have been …

Background Aortic regurgitation (AR) occurs commonly in patients with continuous-flow left
ventricular assist devices (LVAD). No gold standard is available to assess AR severity in this …

The expanding use of continuous‐flow left ventricular assist devices (CF‐LVADs) for end‐
stage heart failure warrants familiarity with the physiologic interaction of the device with the …