Mechanical stimulation utilizing deep tissue-penetrating and focusable energy sources,
such as ultrasound and magnetic fields, is regarded as an emerging patient-friendly and …

Recent findings about cell fate change induced by physical stimuli have expedited the
discovery of underlying regulatory mechanisms that determine stem cell differentiation …

During mesenchymal development, the sources of mechanical forces transduced by cells
transition over time from predominantly cell-cell interactions to predominantly cell …

Artificial bioactive materials have received increasing attention worldwide in clinical
orthopedics to repair bone defects that are caused by trauma, infections or tumors …

One of the major issues in tissue engineering is regulation of stem cell differentiation toward
specific lineages. Unlike biological and chemical signals, physical signals with adjustable …

Photoregulation, which utilizes light to remotely control biological events, provides a precise
way to decipher biology and innovate in medicine; however, its potential is limited by the …

Abnormal mechanical loading often leads to the progressive degradation of cartilage and
causes osteoarthritis (OA). Although multiple mechanoresponsive strategies based on …

In natural microenvironment, various proteins containing adhesive ligands in fibrous and
non‐fibrous structures dynamically couple and decouple to regulate stem cell fate. Herein …

Macrophages regulate host responses to implants through their dynamic adhesion, release,
and activation. Herein, we employ bisphosphonate (BP)-coated gold nanoparticle template …

Purpose Methacrylic anhydride-modified gelatin (GelMA) hydrogels exhibit many beneficial
biological features and are widely studied for bone tissue regeneration. However …