The granulosa cell (GC) is a critical somatic component of the ovary. It is essential for follicle
development by supporting the developing oocyte, proliferating and producing sex steroids …

In vertebrate species that ovulate one or a limited number of ovarian follicles per
reproductive cycle, the cellular processes by which follicle selection (cyclic recruitment) is …

Objective To study the effect of aging and granulosa cell growth hormone receptor (GHR)
expression, and the effect of growth hormone (GH) co-treatment during IVF on receptor …

Using human embryonic stem cells (hESCs), we describe a novel method for the rapid
derivation and enrichment of cells that are comparable to primordial germ cells (PGCs) and …

Background Gonadotropins induce follicular development that leads to ovulation and
luteinization. In women, the level of gonadotropins, along with the expression of their …

In multicellular organisms, cell-cell interactions are mediated in part by cell junctions, which
underlie tissue architecture. Throughout spermatogenesis, for instance, preleptotene …

Accurate determination of estrus is essentially required for efficient reproduction
management of farm animals. Buffalo is a shy breeder and does not manifest overt signs of …

The pig is an agriculturally important species, so understanding its follicular dynamics and
the transcriptional events that accompany such changes is critical to optimizing reproductive …

The poor oocyte quality in older women has previously been linked to the depletion of the
ovarian reserve of primordial follicles and an increase in granulosal apoptosis. Granulosa …

Much has been learned in recent years about the central mechanisms controlling the
initiation of mammalian puberty. It is now clear that this process requires the interactive …