Bioinformatic tools for microRNA dissection
Recently, microRNAs (miRNAs) have emerged as important elements of gene regulatory
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …
[HTML][HTML] Genetic variation in the non-coding genome: Involvement of micro-RNAs and long non-coding RNAs in disease
It has been found that the majority of disease-associated genetic variants identified by
genome-wide association studies are located outside of protein-coding regions, where they …
genome-wide association studies are located outside of protein-coding regions, where they …
The FUS/circEZH2/KLF5/feedback loop contributes to CXCR4-induced liver metastasis of breast cancer by enhancing epithelial-mesenchymal transition
P Liu, Z Wang, X Ou, P Wu, Y Zhang, S Wu, X Xiao… - Molecular cancer, 2022 - Springer
Background Metastasis of breast cancer have caused the majority of cancer-related death
worldwide. The circRNAs are associated with tumorigenesis and metastasis in breast cancer …
worldwide. The circRNAs are associated with tumorigenesis and metastasis in breast cancer …
mirDIP 4.1—integrative database of human microRNA target predictions
MicroRNAs are important regulators of gene expression, achieved by binding to the gene to
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …
be regulated. Even with modern high-throughput technologies, it is laborious and expensive …
Predicting effective microRNA target sites in mammalian mRNAs
MicroRNA targets are often recognized through pairing between the miRNA seed region
and complementary sites within target mRNAs, but not all of these canonical sites are …
and complementary sites within target mRNAs, but not all of these canonical sites are …
Circular RNA circHIPK3 modulates autophagy via MIR124-3p-STAT3-PRKAA/AMPKα signaling in STK11 mutant lung cancer
X Chen, R Mao, W Su, X Yang, Q Geng, C Guo… - Autophagy, 2020 - Taylor & Francis
The role of circular RNA in cancer is emerging. A newly reported circular RNA HIPK3
(circHIPK3) is critical in cell proliferation of various cancer types, although its role in non …
(circHIPK3) is critical in cell proliferation of various cancer types, although its role in non …
Deconstructing transcriptional heterogeneity in pluripotent stem cells
Pluripotent stem cells (PSCs) are capable of dynamic interconversion between distinct
substates; however, the regulatory circuits specifying these states and enabling transitions …
substates; however, the regulatory circuits specifying these states and enabling transitions …
[HTML][HTML] Role of miR-2392 in driving SARS-CoV-2 infection
MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene
regulation that have a major impact on many diseases and provide an exciting avenue …
regulation that have a major impact on many diseases and provide an exciting avenue …
lncRNASNP v3: an updated database for functional variants in long non-coding RNAs
Y Yang, D Wang, YR Miao, X Wu, H Luo… - Nucleic Acids …, 2023 - academic.oup.com
Long non-coding RNAs (lncRNAs) act as versatile regulators of many biological processes
and play vital roles in various diseases. lncRNASNP is dedicated to providing a …
and play vital roles in various diseases. lncRNASNP is dedicated to providing a …
[HTML][HTML] Exosomes from bulk and stem cells from human prostate cancer have a differential microRNA content that contributes cooperatively over local and pre …
CA Sánchez, EI Andahur, R Valenzuela, EA Castellón… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The different prostate cancer (PCa) cell populations (bulk and cancer stem cells, CSCs)
release exosomes that contain miRNAs that could modify the local or premetastatic niche …
release exosomes that contain miRNAs that could modify the local or premetastatic niche …