Liver ischaemia–reperfusion injury (LIRI), a local sterile inflammatory response driven by
innate immunity, is one of the primary causes of early organ dysfunction and failure after …

Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …

Palmitic acid is a saturated fatty acid whose blood concentration is elevated in obese
patients. This causes inflammatory responses, where toll-like receptors (TLR), TLR2 and …

Periodontitis is a common type of inflammatory bone loss and a risk factor for systemic
diseases. The pathogenesis of periodontitis involves inflammatory dysregulation, which …

The immunogenicity of cancer cells is an emerging determinant of anti‐cancer
immunotherapy. Beyond developing immunostimulatory regimens like dendritic cell‐based …

Complex genetic and physiological variations as well as environmental factors that drive
emergence of chromosomal instability, development of unscheduled cell death, skewed …

Acute kidney injury (AKI) due to renal ischemia reperfusion (IR) is a major clinical problem
without effective therapy and is a significant and frequent cause of morbidity and mortality …

Although it was thought that apoptotic cells, when rapidly phagocytosed, underwent a silent
death that did not trigger an immune response, in recent years a new concept of …

Neutrophil extracellular traps (NETs) promote atherosclerosis by inducing proinflammatory
cytokines, but the underlying mechanism remains unknown. NET DNA is immunogenic, but …

Innate immunity plays a crucial role in the response to sterile inflammation such as liver
ischemia/reperfusion (I/R) injury. The initiation of liver I/R injury results in the release of …