Singlet oxygen (1O2) is a biologically relevant reactive oxygen species capable of efficiently
reacting with cellular constituents. The resulting oxidatively generated damage to nucleic …

Endogenous and exogenous sources cause free radical-induced DNA damage in living
organisms by a variety of mechanisms. The highly reactive hydroxyl radical reacts with the …

Oxidative DNA damage is an inevitable consequence of cellular metabolism, with a
propensity for increased levels following toxic insult. Although more than 20 base lesions …

The generation of reactive oxygen species may be both beneficial to cells, performing a
function in inter-and intracellular signalling, and detrimental, modifying cellular …

Oxidatively induced DNA damage is caused in living organisms by endogenous and
exogenous reactive species. DNA lesions resulting from this type of damage are mutagenic …

Endogenous and exogenous sources cause oxidatively induced DNA damage in living
organisms by a variety of mechanisms. The resulting DNA lesions are mutagenic and …

A guanine radical cation (G+•) was site-selectively generated in double stranded DNA and
the charge transfer in different oligonucleotide sequences was investigated. The method is …

In living tissues under inflammatory conditions, superoxide radicals (O 2−⋅) are generated
and are known to cause oxidative DNA damage. However, the mechanisms of action are …

Background: The genome is constantly assaulted by oxidation reactions which are likely to
be associated with oxygen metabolism, and oxidative lesions are generated by many types …

By far the most comprehensive review of the synthesis and reactions of mononuclear
oxazoles and derivatives is The Chemistry of Heterocyclic Compounds, Volume 45, edited …