Glioblastoma is the most lethal brain cancer in adults, with no known cure. This cancer is
characterized by a pronounced genetic heterogeneity, but aberrant activation of receptor …

Simple Summary Considering the high mortality rate and the increasing spread of brain
tumors both in adulthood and in childhood, we explore the role and involvement of fibroblast …

Multiple sclerosis is a demyelinating disease that affects∼ 2,000,000 people worldwide. In
the advanced stages of the disease, endogenous oligodendrocyte precursors cannot …

Fibroblast growth factors (FGFs) and their receptors (FGFRs) constitute signaling circuits that
transmit signals across the plasma membrane, regulating pivotal cellular processes like …

Besides giving rise to oligodendrocytes (the only myelin-forming cell in the Central Nervous
System (CNS) in physiological conditions), Oligodendrocyte Precursor Cells (OPCs) are …

Background The accumulation of activated microglia is a hallmark of various
neurodegenerative diseases. Microglia may have both protective and toxic effects on …

FGF2 is considered a key factor in the generation of oligodendrocytes (OLs) derived from
neural stem cells (NSCs) located within the subventricular zone (SVZ). Here, we have …

CHARGE is a multiple congenital anomaly disorder and a common cause of pubertal
defects, olfactory dysfunction, growth delays, deaf-blindness, balance disorders and …

The sense of smell plays a crucial role in the sensory world of animals. Two chemosensory
systems have been traditionally thought to play-independent roles in mammalian olfaction …

Fibroblast growth factor (FGF) signaling is involved in a multitude of biological processes,
while impairment of FGF signaling is implicated in a variety of human diseases including …