The discovery of several unexpected complex biological roles of hyaluronic acid (HA) has
promoted new research impetus for biologists and, the clinical interest in several fields of …

Osteoarthritis is the most common degenerative and highly prevalent joint disease,
characterized by progressive loss and destruction of articular cartilage. The damaged …

The early stages of progressive degeneration of cartilage in articular joints are a hallmark of
osteoarthritis. Healthy cartilage is lubricated by brush-like cartilage-binding nanofibres with …

Hydration lubrication has emerged as a new paradigm for lubrication in aqueous and
biological media, accounting especially for the extremely low friction (friction coefficients …

Lubrication is everywhere in the body and essential for the correct operation of biological
systems when subjected to contact stress and wear. The body is like a continuously …

When lubricated by synovial fluid, articular cartilage provides some of the lowest friction
coefficients found in nature. While it is known that macromolecular constituents of synovial …

Rheumatoid arthritis (RA) is a chronic inflammatory immune and lubrication dysfunction
disease that causes great damage to the joints. Herein, inspired by the unique biochemistry …

Herein, we systematically investigate the origin of astringent mouthfeel when we eat unripe
fruits, drink coffee or tea, from the perspective of lubrication by simulating the dynamic weak …

The remarkable lubrication properties of normal articular cartilage play an essential role in
daily life, providing almost frictionless movements of joints. Alterations of cartilage surface or …

Articular cartilage provides ultralow friction to maintain the physiological function of the knee
joint, which arises from the hierarchical complex composed of hyaluronic acid …