Mounting evidence suggests that the gut microbiome impacts brain development and
function. Gut–brain connections may be mediated by an assortment of microbial molecules …

Highlights•Sixteen leading groups review evidence for the therapeutic effects of
agmatine.•Agmatine modulatory action at multiple molecular targets is highlighted.• …

This paper reviews and interprets a method for determining the nutritional value of d-amino
acids, d-peptides, and amino acid derivatives using a growth assay in mice fed a synthetic …

Agmatine, an endogenous polyamine derived from L-arginine, elicits tremendous
multimodal neuromodulant properties. Alterations in agmatinergic signalling are closely …

Agmatine, the decarboxylation product of arginine, was largely neglected as an important
player in mammalian metabolism until the mid-1990s, when it was re-discovered as an …

Agmatine is a polyamine that is produced via decarboxylation of l-arginine by the enzyme
arginine decarboxylase. It binds to various receptors and has been accepted as a novel …

The role of norepinephrine (NE) in the development of alcohol use disorder (AUD) has been
studied over the past several decades. However, the NE system has been largely ignored …

Agmatine, a cationic amine formed by decarboxylation of l-arginine by the mitochondrial
enzyme arginine decarboxylase (ADC), is widely but unevenly distributed in mammalian …

Our analysis shows that there is a large interest in performing anxiety research innovatively.
However, efforts are highly divergent and result in large numbers of poorly validated and …

Chronic maternal ethanol exposure leads to poor intelligence, impaired cognition and array
of neurological symptoms in offsprings and commonly referred as fetal alcohol spectrum …