[HTML][HTML] ACE2 in chronic disease and COVID-19: gene regulation and post-translational modification
CW Wang, HC Chuang, TH Tan - Journal of Biomedical Science, 2023 - Springer
Abstract Angiotensin-converting enzyme 2 (ACE2), a counter regulator of the renin-
angiotensin system, provides protection against several chronic diseases. Besides chronic …
angiotensin system, provides protection against several chronic diseases. Besides chronic …
[HTML][HTML] Mechanisms leading to gut dysbiosis in COVID-19: current evidence and uncertainties based on adverse outcome pathways
LA Clerbaux, J Filipovska, A Muñoz, M Petrillo… - Journal of clinical …, 2022 - mdpi.com
Alteration in gut microbiota has been associated with COVID-19. However, the underlying
mechanisms remain poorly understood. Here, we outlined three potential interconnected …
mechanisms remain poorly understood. Here, we outlined three potential interconnected …
[HTML][HTML] COVID-19: biologic and immunosuppressive therapy in gastroenterology and hepatology
MF Neurath - Nature Reviews Gastroenterology & Hepatology, 2021 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic is an ongoing global health
crisis causing major challenges for clinical care in patients with gastrointestinal diseases …
crisis causing major challenges for clinical care in patients with gastrointestinal diseases …
Bioadhesive microcarriers encapsulated with IL‐27 high expressive MSC extracellular vesicles for inflammatory bowel disease treatment
Mesenchymal stem cell (MSC) therapy is a promising candidate for inflammatory bowel
disease (IBD) treatment, while overcoming the limitations of naive seeding cells function and …
disease (IBD) treatment, while overcoming the limitations of naive seeding cells function and …
Bile acids and bile acid activated receptors in the treatment of Covid-19
Since its first outbreak in 2020, the pandemic caused by the Severe Acute Respiratory
Syndrome-Coronavirus-2 (SARS-CoV-2) has caused the death of almost 7 million people …
Syndrome-Coronavirus-2 (SARS-CoV-2) has caused the death of almost 7 million people …
Inflammatory bowel disease clinical activity is associated with COVID-19 severity especially in younger patients
A Ricciuto, CA Lamb, EI Benchimol… - Journal of Crohn's …, 2022 - academic.oup.com
Abstract Background and Aims Age is a major prognostic factor for COVID-19 outcomes. The
effect of inflammatory bowel disease [IBD] activity on COVID-19 is unclear. We examined the …
effect of inflammatory bowel disease [IBD] activity on COVID-19 is unclear. We examined the …
Immunology of bile acids regulated receptors
Bile acids are steroids generated at the interface of host and intestinal microbiota. While
primary bile acids are generated in the liver from cholesterol metabolism, secondary bile …
primary bile acids are generated in the liver from cholesterol metabolism, secondary bile …
[HTML][HTML] Variable susceptibility of intestinal organoid–derived monolayers to SARS-CoV-2 infection
Gastrointestinal effects associated with Coronavirus Disease 2019 (COVID-19) are highly
variable for reasons that are not understood. In this study, we used intestinal organoid …
variable for reasons that are not understood. In this study, we used intestinal organoid …
[HTML][HTML] Molecular insights into SARS-CoV2-induced alterations of the gut/brain axis
S Nataf, L Pays - International Journal of Molecular Sciences, 2021 - mdpi.com
For a yet unknown reason, a substantial share of patients suffering from COVID-19 develop
long-lasting neuropsychiatric symptoms ranging from cognitive deficits to mood disorders …
long-lasting neuropsychiatric symptoms ranging from cognitive deficits to mood disorders …
[HTML][HTML] Hypothesis: Emerging roles for aryl hydrocarbon receptor in orchestrating CoV-2-related inflammation
T Guarnieri - Cells, 2022 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is the pathogenic agent
of Coronavirus-Induced Disease-2019 (COVID-19), a multi-organ syndrome which primarily …
of Coronavirus-Induced Disease-2019 (COVID-19), a multi-organ syndrome which primarily …