Methods for direct alkene diamination, new & old
S De Jong, DG Nosal, DJ Wardrop - Tetrahedron, 2012 - Elsevier
The 1, 2-diamine moiety is an ubiquitous structural motif found in a wealth of natural
products, including non-proteinogenic amino acids and alkaloids, in pharmaceutical agents …
products, including non-proteinogenic amino acids and alkaloids, in pharmaceutical agents …
Phytochemicals as antiviral agents: recent updates
R Ghildiyal, V Prakash, VK Chaudhary, V Gupta… - Plant-derived bioactives …, 2020 - Springer
The epidemic of viral diseases is a global concern, mandating an urgent need of most
promising antivirals. Some of the viral diseases can be cured by approved antiviral drugs …
promising antivirals. Some of the viral diseases can be cured by approved antiviral drugs …
Synthesis of Chiral Vicinal Diamines by Silver (I)‐Catalyzed Enantioselective Aminolysis of N‐Tosylaziridines
Z Chai, PJ Yang, H Zhang, S Wang… - Angewandte …, 2017 - Wiley Online Library
The kinetic resolution of 2‐aryl‐N‐tosylaziridines and the asymmetric desymmetrization of
meso‐N‐tosylaziridines by ring openings with various primary and secondary anilines, and …
meso‐N‐tosylaziridines by ring openings with various primary and secondary anilines, and …
Polyanionic carbosilane dendrimers prevent hepatitis C virus infection in cell culture
D Sepúlveda-Crespo, JL Jiménez, R Gómez… - … , Biology and Medicine, 2017 - Elsevier
Hepatitis C virus (HCV) infection is a major biomedical problem worldwide. Although new
direct antiviral agents (DAAs) have been developed for the treatment of chronic HCV …
direct antiviral agents (DAAs) have been developed for the treatment of chronic HCV …
Sigma-1 receptor regulates early steps of viral RNA replication at the onset of hepatitis C virus infection
M Friesland, L Mingorance, J Chung, FV Chisari… - Journal of …, 2013 - Am Soc Microbiol
Hepatitis C virus (HCV) genome replication is thought to occur in a membranous cellular
compartment derived from the endoplasmic reticulum (ER). The molecular mechanisms by …
compartment derived from the endoplasmic reticulum (ER). The molecular mechanisms by …
[HTML][HTML] Cell Penetrable Humanized-VH/VHH That Inhibit RNA Dependent RNA Polymerase (NS5B) of HCV
K Thueng-In, J Thanongsaksrikul, P Srimanote… - PLoS …, 2012 - journals.plos.org
NS5B is pivotal RNA dependent RNA polymerase (RdRp) of HCV and NS5B function
interfering halts the virus infective cycle. This work aimed to produce cell penetrable …
interfering halts the virus infective cycle. This work aimed to produce cell penetrable …
[HTML][HTML] Self-assembling peptide nanotubes with antiviral activity against hepatitis C virus
A Montero, P Gastaminza, M Law, G Cheng… - Chemistry & biology, 2011 - cell.com
Hepatitis C virus (HCV) infects chronically 3% of the world population and the current
therapy against this pathogen is only partially effective. With the aim of developing novel …
therapy against this pathogen is only partially effective. With the aim of developing novel …
Selective inhibition of hepatitis C virus infection by hydroxyzine and benztropine
L Mingorance, M Friesland… - Antimicrobial agents …, 2014 - Am Soc Microbiol
Hepatitis C virus (HCV) infection is a major biomedical problem worldwide as it causes
severe liver disease in millions of humans around the world. Despite the recent approval of …
severe liver disease in millions of humans around the world. Despite the recent approval of …
Y-box binding protein 1 stabilizes hepatitis C virus NS5A via phosphorylation-mediated interaction with NS5A to regulate viral propagation
WT Wang, TY Tsai, CH Chao, BY Lai… - Journal of …, 2015 - Am Soc Microbiol
Replication of hepatitis C virus (HCV) is dependent on virus-encoded proteins and
numerous cellular factors. DDX3 is a well-known host cofactor of HCV replication. In this …
numerous cellular factors. DDX3 is a well-known host cofactor of HCV replication. In this …
[PDF][PDF] Medicinal and aromatic plants: A potential source of novel bioactive compounds showing antiviral efficacy against coronavirus (SARS-CoV-2)
COVID-19 outbreak is a common respiratory tract infection in humans primarily caused by a
new type of virus SARS-CoV-2 (2019-nCoV) started in 2019 and spread quickly within the …
new type of virus SARS-CoV-2 (2019-nCoV) started in 2019 and spread quickly within the …