ATR-FTIR spectroscopic imaging: recent advances and applications to biological systems

SG Kazarian, KLA Chan - Analyst, 2013 - pubs.rsc.org
Attenuated total reflection Fourier transform infrared (ATR-FTIR) spectroscopic imaging is a
highly versatile, label free and non-destructive chemical imaging method which can be …

Role of infrared spectroscopy and imaging in cancer diagnosis

S Kumar, A Srinivasan… - Current medicinal …, 2018 - ingentaconnect.com
Background: Cancer is a major global health issue. It causes extensive individual suffering
and gives a huge burden on the health care in society. Despite extensive research and …

Infrared-spectroscopic, dynamic near-field microscopy of living cells and nanoparticles in water

KJ Kaltenecker, T Gölz, E Bau, F Keilmann - Scientific reports, 2021 - nature.com
Infrared fingerprint spectra can reveal the chemical nature of materials down to 20-nm detail,
far below the diffraction limit, when probed by scattering-type scanning near-field optical …

Near-field imaging and nano-Fourier-transform infrared spectroscopy using broadband synchrotron radiation

P Hermann, A Hoehl, P Patoka, F Huth, E Rühl… - Optics express, 2013 - opg.optica.org
We demonstrate scanning near-field optical microscopy with a spatial resolution below 100
nm by using low intensity broadband synchrotron radiation in the IR regime. The use of such …

Rapid approach to analyze biochemical variation in rat organs by ATR FTIR spectroscopy

E Staniszewska, K Malek, M Baranska - Spectrochimica Acta Part A …, 2014 - Elsevier
ATR FTIR spectra were collected from rat tissue homogenates (myocardium, brain, liver,
lung, intestine, and kidney) to analyze their biochemical content. Based on the second …

Contribution of ribonucleic acid (RNA) to the Fourier transform infrared (FTIR) spectrum of eukaryotic cells

P Zucchiatti, E Mitri, S Kenig, F Billè… - Analytical …, 2016 - ACS Publications
We report on an optimized protocol for the digestion of cellular RNA, which minimally affects
the cell membrane integrity, maintaining substantially unaltered the vibrational contributions …

Long-term, non-invasive FTIR detection of low-dose ionizing radiation exposure

JL Inman, Y Wu, L Chen, E Brydon, D Ghosh… - Scientific Reports, 2024 - nature.com
Non-invasive methods of detecting radiation exposure show promise to improve upon
current approaches to biological dosimetry in ease, speed, and accuracy. Here we …

FTIR imaging of tissues: techniques and methods of analysis

K Malek, BR Wood, KR Bambery - Optical spectroscopy and …, 2014 - Springer
In this chapter, we describe biomedical applications of infrared microscopic imaging applied
to human tissue sections. The central focus is human diseases including cervical cancer …

FTIR spectral signature of anticancer drugs. Can drug mode of action be identified?

A Mignolet, A Derenne, M Smolina, BR Wood… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Infrared spectroscopy has brought invaluable information about proteins and about the
mechanism of action of enzymes. These achievements are difficult to transpose to living …

Metasurface-enhanced infrared spectroscopy in multiwell format for real-time assaying of live cells

SH Huang, G Sartorello, PT Shen, C Xu, O Elemento… - Lab on a Chip, 2023 - pubs.rsc.org
Fourier transform infrared (FTIR) spectroscopy is a popular technique for the analysis of
biological samples, yet its application in characterizing live cells is limited due to the strong …