miRNAs as Cornerstones in Chronic Lymphocytic Leukemia Pathogenesis and Therapeutic Resistance–An emphasis on the interaction of signaling pathways
Chronic lymphocytic leukemia (CLL) accounts for the vast majority of cases of leukemia.
Patients of advanced age are more likely to develop the condition, which has a highly varied …
Patients of advanced age are more likely to develop the condition, which has a highly varied …
The pervasive role of the miR-181 family in development, neurodegeneration, and cancer
MicroRNAs (miRNAs) are small noncoding RNAs playing a fundamental role in the
regulation of gene expression. Evidence accumulating in the past decades indicate that they …
regulation of gene expression. Evidence accumulating in the past decades indicate that they …
MicroRNA-181b regulates NF-κB–mediated vascular inflammation
X Sun, B Icli, AK Wara, N Belkin, S He… - The Journal of …, 2012 - Am Soc Clin Investig
EC activation and dysfunction have been linked to a variety of vascular inflammatory
disease states. The function of microRNAs (miRNAs) in vascular EC activation and …
disease states. The function of microRNAs (miRNAs) in vascular EC activation and …
Dysregulation of a family of short noncoding RNAs, tsRNAs, in human cancer
Chronic lymphocytic leukemia (CLL) is the most common human leukemia, and transgenic
mouse studies indicate that activation of the T-cell leukemia/lymphoma 1 (TCL1) oncogene …
mouse studies indicate that activation of the T-cell leukemia/lymphoma 1 (TCL1) oncogene …
MicroRNAs in B-cell lymphomas: how a complex biology gets more complex
K Musilová, M Mráz - Leukemia, 2015 - nature.com
MicroRNAs (miRNAs) represent important regulators of gene expression besides
transcriptional control. miRNA regulation can be involved in the cell developmental fate …
transcriptional control. miRNA regulation can be involved in the cell developmental fate …
[HTML][HTML] Targeting oncomiRNAs and mimicking tumor suppressor miRNAs: Νew trends in the development of miRNA therapeutic strategies in oncology
R Gambari, E Brognara… - … journal of oncology, 2016 - spandidos-publications.com
MicroRNA (miRNA or miR) therapeutics in cancer are based on targeting or mimicking
miRNAs involved in cancer onset, progression, angiogenesis, epithelial-mesenchymal …
miRNAs involved in cancer onset, progression, angiogenesis, epithelial-mesenchymal …
Clinical significance of microRNAs in chronic and acute human leukemia
Small non-coding microRNAs (miRNAs) are epigenetic regulators that target specific cellular
mRNA to modulate gene expression patterns and cellular signaling pathways. miRNAs are …
mRNA to modulate gene expression patterns and cellular signaling pathways. miRNAs are …
The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness
B Bao, AS Azmi, S Ali, A Ahmad, Y Li… - … et Biophysica Acta (BBA …, 2012 - Elsevier
Hypoxia is one of the fundamental biological phenomena that are intricately associated with
the development and aggressiveness of a variety of solid tumors. Hypoxia-inducible factors …
the development and aggressiveness of a variety of solid tumors. Hypoxia-inducible factors …
miR-150 influences B-cell receptor signaling in chronic lymphocytic leukemia by regulating expression of GAB1 and FOXP1
We examined the microRNAs (miRNAs) expressed in chronic lymphocytic leukemia (CLL)
and identified miR-150 as the most abundant, but with leukemia cell expression levels that …
and identified miR-150 as the most abundant, but with leukemia cell expression levels that …
Distinct microRNA expression profiles in prostate cancer stem/progenitor cells and tumor-suppressive functions of let-7
C Liu, K Kelnar, AV Vlassov, D Brown, J Wang… - Cancer research, 2012 - AACR
MiRNAs regulate cancer cells, but their potential effects on cancer stem/progenitor cells are
still being explored. In this study, we used quantitative real-time-PCR to define miRNA …
still being explored. In this study, we used quantitative real-time-PCR to define miRNA …