Plasmodium vivax is the most widespread human malaria, putting 2.5 billion people at risk of
infection. Its unique biological and epidemiological characteristics pose challenges to …

Most Plasmodium falciparum infections that are detected in community surveys are
characterized by low-density parasitaemia and the absence of clinical symptoms. Molecular …

Malaria-eliminating countries achieved remarkable success in reducing their malaria
burdens between 2000 and 2010. As a result, the epidemiology of malaria in these settings …

Scale-up of malaria control interventions has resulted in a substantial decline in global
malaria morbidity and mortality. Despite this achievement, there is evidence that current …

Introduction Light microscopy examination of blood slides is the main method of detecting
malaria infection; however, it has limited sensitivity. Low-density infections are most likely to …

Malaria is still a major public health problem in Brazil, with approximately 306 000 registered
cases in 2009, but it is estimated that in the early 1940s, around six million cases of malaria …

Hugh Sturrock and colleagues discuss the role of active case detection in low malaria
transmission settings. They argue that the evidence for its effectiveness is sparse and that …

Brazil currently contributes 42% of all malaria cases reported in the Latin America and the
Caribbean, a region where major progress towards malaria elimination has been achieved …

Malaria is a serious parasitic disease in the developing world, causing high morbidity and
mortality. The pathogenesis of malaria is complex, and the clinical presentation of disease …

Achieving malaria elimination requires targeting the human reservoir of infection, including
those with asymptomatic infection. Smear-positive asymptomatic infections detectable by …