[HTML][HTML] A role for microfluidic systems in precision medicine
JM Ayuso, M Virumbrales-Muñoz, JM Lang… - Nature …, 2022 - nature.com
Precision oncology continues to challenge the “one-size-fits-all” dogma. Under the precision
oncology banner, cancer patients are screened for molecular tumor alterations that predict …
oncology banner, cancer patients are screened for molecular tumor alterations that predict …
[HTML][HTML] Viscoelastic microfluidics: Progress and challenges
J Zhou, I Papautsky - Microsystems & Nanoengineering, 2020 - nature.com
The manipulation of cells and particles suspended in viscoelastic fluids in microchannels
has drawn increasing attention, in part due to the ability for single-stream three-dimensional …
has drawn increasing attention, in part due to the ability for single-stream three-dimensional …
Detection of circulating tumor cells and their implications as a biomarker for diagnosis, prognostication, and therapeutic monitoring in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is among the leading causes of worldwide cancer‐related
morbidity and mortality. Poor prognosis of HCC is attributed primarily to tumor presentation …
morbidity and mortality. Poor prognosis of HCC is attributed primarily to tumor presentation …
[HTML][HTML] Biomedical applications of microfluidic devices: a review
Both passive and active microfluidic chips are used in many biomedical and chemical
applications to support fluid mixing, particle manipulations, and signal detection. Passive …
applications to support fluid mixing, particle manipulations, and signal detection. Passive …
Fundamentals and applications of inertial microfluidics: A review
In the last decade, inertial microfluidics has attracted significant attention and a wide variety
of channel designs that focus, concentrate and separate particles and fluids have been …
of channel designs that focus, concentrate and separate particles and fluids have been …
Channel innovations for inertial microfluidics
W Tang, S Zhu, D Jiang, L Zhu, J Yang, N Xiang - Lab on a Chip, 2020 - pubs.rsc.org
Inertial microfluidics has gained significant attention since first being proposed in 2007
owing to the advantages of simplicity, high throughput, precise manipulation, and freedom …
owing to the advantages of simplicity, high throughput, precise manipulation, and freedom …
Microfluidic cell sorting: a review of the advances in the separation of cells from debulking to rare cell isolation
CW Shields Iv, CD Reyes, GP López - Lab on a Chip, 2015 - pubs.rsc.org
Accurate and high throughput cell sorting is a critical enabling technology in molecular and
cellular biology, biotechnology, and medicine. While conventional methods can provide high …
cellular biology, biotechnology, and medicine. While conventional methods can provide high …
[HTML][HTML] Circulating tumor cell technologies
MM Ferreira, VC Ramani, SS Jeffrey - Molecular oncology, 2016 - Elsevier
Circulating tumor cells, a component of the “liquid biopsy”, hold great potential to transform
the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of …
the current landscape of cancer therapy. A key challenge to unlocking the clinical utility of …
Ultra-fast, label-free isolation of circulating tumor cells from blood using spiral microfluidics
Circulating tumor cells (CTCs) are rare cancer cells that are shed from primary or metastatic
tumors into the peripheral blood circulation. Phenotypic and genetic characterization of …
tumors into the peripheral blood circulation. Phenotypic and genetic characterization of …
A review of sorting, separation and isolation of cells and microbeads for biomedical applications: microfluidic approaches
Several biomedical analyses are performed on particular types of cells present in body
samples or using functionalized microparticles. Success in such analyses depends on the …
samples or using functionalized microparticles. Success in such analyses depends on the …