Mice thermoneutral zone lies at temperatures much higher than expected when considering
the geographical extension of the species. Growing evidence shows that mouse-dependent …

Animals have been used in research for over 2,000 y. From very crude experiments
conducted by ancient scholars, animal research, as a science, was refined over hundreds of …

Abstract Narcolepsy type 1 (NT1), characterized by the loss of hypocretin/orexin (HCRT)
production in the lateral hypothalamus, has been linked to Pandemrix vaccination during the …

Psycho-environmental stress-based animal models of anxiety and depression are useful for
investigating pathological mechanisms and drug development. Although several rodent …

Objective animal health evaluation is essential to determine welfare and discomfort in
preclinical in vivo research. Body condition scores, body weight, and grimace scales are …

Feed wastage in laboratory mice, also known as chewing or grinding behavior, is
problematic for program management and animal welfare. The destruction of pelleted feed …

The brain, functionally dominated by neurons, relies on the support of non-neuronal cells for
optimal function. Astrocytes play an important role in this system, such as by engaging with …

Neurodevelopmental psychiatric disorders (NPDs), such as attention deficit hyperactivity
disorder (ADHD), autism spectrum disorder (ASD), and schizophrenia (SCZ), and their …

Arachidonsäurelipoxygenasen (ALOX-Isoformen) sind Lipid-peroxidierenden Enzyme, die
bei der Zelldifferenzierung und bei der Pathogenese verschiedener Erkrankungen …

Preanalytical variability in animals, v2 05. Laboratory animals 2. Mouse Page 1 1 Preanalytical
variability in animals, v2 05. Laboratory animals 2. Mouse N. Bourges-Abella, F. Granat, A …