[HTML][HTML] The mRNA-LNP platform's lipid nanoparticle component used in preclinical vaccine studies is highly inflammatory
Vaccines based on mRNA-containing lipid nanoparticles (LNPs) are a promising new
platform used by two leading vaccines against COVID-19. Clinical trials and ongoing …
platform used by two leading vaccines against COVID-19. Clinical trials and ongoing …
The roles of skin Langerhans cells in immune tolerance and cancer immunity
Langerhans cells (LC) are a unique population of tissue-resident macrophages with
dendritic cell (DC) functionality that form a network of cells across the epidermis of the skin …
dendritic cell (DC) functionality that form a network of cells across the epidermis of the skin …
[HTML][HTML] Rethinking the pathogenesis of cutaneous lupus
JM Kahlenberg - Journal of Investigative Dermatology, 2021 - Elsevier
Knowledge of the etiology of cutaneous lupus is rapidly evolving. Dissection of the
pathologic events in lesional skin has led to knowledge of important cell populations and …
pathologic events in lesional skin has led to knowledge of important cell populations and …
Early antitumor activity of oral Langerhans cells is compromised by a carcinogen
Y Saba, I Aizenbud, D Matanes… - Proceedings of the …, 2022 - National Acad Sciences
Early diagnosis of oral squamous cell carcinoma (OSCC) remains an unmet clinical need.
Therefore, elucidating the initial events of OSCC preceding tumor development could benefit …
Therefore, elucidating the initial events of OSCC preceding tumor development could benefit …
Zebrafish cutaneous injury models reveal that Langerhans cells engulf axonal debris in adult epidermis
E Peterman, EJA Quitevis, EC Black… - Disease Models & …, 2023 - journals.biologists.com
Somatosensory neurons extend enormous peripheral axons to the skin, where they detect
diverse environmental stimuli. Somatosensory peripheral axons are easily damaged due to …
diverse environmental stimuli. Somatosensory peripheral axons are easily damaged due to …
Recent advances in cutaneous lupus
MP Maz, JWS Martens, A Hannoudi, AL Reddy… - Journal of …, 2022 - Elsevier
Cutaneous lupus erythematosus (CLE) is an inflammatory and autoimmune skin condition
that affects patients with systemic lupus erythematosus (SLE) and exists as an isolated entity …
that affects patients with systemic lupus erythematosus (SLE) and exists as an isolated entity …
Epidermal maintenance of Langerhans cells relies on autophagy-regulated lipid metabolism
F Arbogast, R Sal-Carro, W Boufenghour, Q Frenger… - bioRxiv, 2022 - biorxiv.org
ABSTRACT Macroautophagy (often-named autophagy), a catabolic process involving
autophagy-related (Atg) genes, prevents accumulation of harmful cytoplasmic components …
autophagy-related (Atg) genes, prevents accumulation of harmful cytoplasmic components …
[PDF][PDF] The Roles of Skin Langerhans Cells in Immune Tolerance and Cancer Immunity. Vaccines 2022, 10, 1380
Langerhans cells (LC) are a unique population of tissue-resident macrophages with
dendritic cell (DC) functionality that form a network of cells across the epidermis of the skin …
dendritic cell (DC) functionality that form a network of cells across the epidermis of the skin …
[HTML][HTML] Meeting Report of the 16th International Langerhans Cell Workshop: Recent Developments in Langerhans Cell and Skin Dendritic Cell Biology and their …
BE Clausen, N Romani, P Stoitzner - Journal of Investigative Dermatology, 2020 - Elsevier
The 16th International Workshop on Langerhans Cells (LCs) was organized by Björn E.
Clausen with the help of Patrizia Stoitzner and Nikolaus Romani in Budenheim near Mainz …
Clausen with the help of Patrizia Stoitzner and Nikolaus Romani in Budenheim near Mainz …