Non-alcoholic fatty liver disease (NAFLD), including non-alcoholic fatty liver (NAFL) and non-
alcoholic steatohepatitis (NASH), represents the hepatic manifestation of obesity and …

Non-alcoholic fatty liver disease (NAFLD) represents a global healthcare challenge,
affecting 1 in 4 adults, and death rates are predicted to rise inexorably. The progressive form …

Within the liver, non-parenchymal cells (NPCs) are critically involved in the regulation of
hepatocyte polarization and maintenance of metabolic function. We here report the …

Acute liver failure can be the consequence of various etiologies, with most cases arising
from drug-induced hepatotoxicity in Western countries. Despite advances in this field, the …

Naturally-derived biomaterials have been used for decades in multiple regenerative
medicine applications. From the simplest cell microcarriers made of collagen or alginate, to …

Cell transplantation is a promising approach for promoting tissue regeneration in the
treatment of damaged tissues or organs. Although cells have conventionally been delivered …

Recent advances in the development of various culture platforms are promising for
achieving more physiologically relevant in vitro hepatic models using primary human …

The liver is a central organ in the human body and first line of defense between host and
external environment. Liver response to any external perturbation is a collective reaction of …

Despite the exciting properties and wide-reaching applications of nanobiomaterials (NBMs)
in human health and medicine, their translation from bench to bedside is slow, with a …

Hepatocyte spheroids microencapsulated in hydrogels can contribute to liver research in
various capacities. The conventional approach of microencapsulating spheroids produces a …