The hallmarks of P arkinson's disease
Since the discovery of dopamine as a neurotransmitter in the 1950s, P arkinson's disease
(PD) research has generated a rich and complex body of knowledge, revealing PD to be an …
(PD) research has generated a rich and complex body of knowledge, revealing PD to be an …
[HTML][HTML] Applications in image-based profiling of perturbations
Highlights•Image-based profiling uses hundreds of measurements of cell morphology from
images.•Samples with similar phenotypes are grouped based on this unbiased, quantitative …
images.•Samples with similar phenotypes are grouped based on this unbiased, quantitative …
[HTML][HTML] Preparing Arabidopsis thaliana root protoplasts for cryo electron tomography
IB Sanchez Carrillo, PC Hoffmann, T Barff… - Frontiers in Plant …, 2023 - frontiersin.org
The use of protoplasts in plant biology has become a convenient tool for the application of
transient gene expression. This model system has allowed the study of plant responses to …
transient gene expression. This model system has allowed the study of plant responses to …
[HTML][HTML] The influence of spatial and temporal resolutions on the analysis of cell-cell interaction: a systematic study for time-lapse microscopy applications
Cell-cell interactions are an observable manifestation of underlying complex biological
processes occurring in response to diversified biochemical stimuli. Recent experiments with …
processes occurring in response to diversified biochemical stimuli. Recent experiments with …
[HTML][HTML] Pre-Implantation Bovine Embryo Evaluation—From Optics to Omics and Beyond
RAC Rabel, PV Marchioretto, EA Bangert, K Wilson… - Animals, 2023 - mdpi.com
Simple Summary With conventional breeding practices, even the best dairy/beef cows will
likely produce no more than half-a-dozen calves in their lifetimes; a crime, would you not …
likely produce no more than half-a-dozen calves in their lifetimes; a crime, would you not …
Design of a 3D printed smartphone microscopic system with enhanced imaging ability for biomedical applications
Portable, low‐cost smartphone platform microscopic systems have emerged as a potential
tool for imaging of various micron and submicron scale particles in recent years (Ozcan; …
tool for imaging of various micron and submicron scale particles in recent years (Ozcan; …
XLuminA: An Auto-differentiating Discovery Framework for Super-Resolution Microscopy
In this work we introduce XLuminA, an original computational framework designed for the
discovery of novel optical hardware in super-resolution microscopy. Our framework offers …
discovery of novel optical hardware in super-resolution microscopy. Our framework offers …
An affordable, handheld multimodal microscopic system with onboard cell morphology and counting features on a mobile device
Microscopes, bright-field (BF) and fluorescence microscopes, in particular, are ubiquitous for
clinical diagnostics, cellular and microbiological investigations and in research laboratories …
clinical diagnostics, cellular and microbiological investigations and in research laboratories …
Programmable illumination smartphone microscopy (PISM): A multimodal imaging platform for biomedical applications
Microscopes on the smartphone platform are handy for a wide range of applications. We
report herein a programmable illumination smartphone microscopy (PISM) as a flexible …
report herein a programmable illumination smartphone microscopy (PISM) as a flexible …
[HTML][HTML] Automated cell boundary and 3D nuclear segmentation of cells in suspension
B Kesler, G Li, A Thiemicke, R Venkat, G Neuert - Scientific reports, 2019 - nature.com
To characterize cell types, cellular functions and intracellular processes, an understanding
of the differences between individual cells is required. Although microscopy approaches …
of the differences between individual cells is required. Although microscopy approaches …