It is well known that gonadotropin-releasing hormone (Gnrh) has a key role in reproduction
by regulating the synthesis and release of gonadotropins from the anterior pituitary gland of …

Teleost fish exhibit remarkably diverse and plastic patterns of sexual development. One of
the most fascinating modes of plasticity is functional sex change, which is widespread in …

Plastic pollution is a growing global emergency and it could serve as a geological indicator
of the Anthropocene era. Microplastics are potentially more hazardous than macroplastics …

The kiss1/gpr54 signaling system is considered to be a critical regulator of reproduction in
most vertebrates. However, this presumption has not been tested vigorously in …

Sexual fate is no longer seen as an irreversible deterministic switch set during early
embryonic development but as an ongoing battle for primacy between male and female …

Reproduction is essential for life, but its regulatory mechanism is diverse. The analysis of
this diversity should lead us to understand the evolutionary process of the regulation of …

The first critical steps in testicular development from the indifferent gonad and subsequent
masculinization of the fetus are differentiation of the Sertoli cells and Leydig cells (Byskov …

Kisspeptin, a novel neuropeptide product of the Kiss1 gene, activates the G protein-coupled
membrane receptor G protein-coupled receptor 54 (now termed Kiss1r). Over the last 15 …

The kisspeptin neuronal system, which consists of a neuropeptide kisspeptin and its
receptor Gpr54, is considered in mammals a key factor of reproductive regulation, the so …

Reproduction is regulated by the hypothalamic-pituitary-gonadal (HPG) axis in vertebrates.
In addition to wealth of knowledge in mammals, recent studies in non-mammalian species …