Background: Limb muscle dysfunction is prevalent in chronic obstructive pulmonary disease
(COPD) and it has important clinical implications, such as reduced exercise tolerance …

Comorbidities such as cardiac disease, diabetes mellitus, hypertension, osteoporosis, and
psychological disorders are commonly reported in patients with chronic obstructive …

Respiratory and/or limb muscle dysfunction, which are frequently observed in chronic
obstructive pulmonary disease (COPD) patients, contribute to their disease prognosis …

Muscle dysfunction often occurs in patients with chronic obstructive pulmonary disease
(COPD) and may involve both respiratory and locomotor (peripheral) muscles. The loss of …

Rationale: Inflammation and oxidative stress contribute to muscle dysfunction in patients
with chronic obstructive pulmonary disease (COPD). Oxidants contained in cigarette smoke …

In the next decade, Chronic Obstructive Pulmonary Disease (COPD) will be a major leading
cause of death worldwide. Impaired muscle function and mass are common systemic …

Chronic obstructive pulmonary disease (COPD) is a debilitating disease characterized by
inflammation-induced airflow limitation and parenchymal destruction. In addition to …

Many patients with chronic obstructive pulmonary disease (COPD) suffer from exercise
intolerance. In about 40% of the patients exercise capacity is limited by alterations in skeletal …

The skeletal muscles play an essential role in life, providing the mechanical basis for
respiration and movement. Skeletal muscle dysfunction is prevalent in all stages of chronic …

Peripheral muscle dysfunction is an important systemic consequence of cystic fibrosis (CF)
with major clinical implications, such as exercise intolerance and reduced quality of life …