Local anesthetic systemic toxicity (LAST) is a life-threatening adverse event that may occur
after the administration of local anesthetic drugs through a variety of routes. Increasing use …

The experimental use of lipid emulsion for local anesthetic toxicity was originally identified in
1998. It was then translated to clinical practice in 2006 and expanded to drugs other than …

Lipid emulsion has been shown to be an effective treatment for systemic toxicity induced by
local anesthetics, which is reflected in case reports. A systemic review and meta-analysis …

Local anesthetics are widely used clinically for perioperative analgesia to achieve comfort in
medical treatment. However, when the concentration of local anesthetics in the blood …

Biodetoxification using intravenous lipid emulsion (ILE) in acute poisoning is of growing
interest. As well as for local anesthetics, ILE is currently used to reverse toxicity caused by a …

Infusion of lipid emulsion for drug overdose arose as a treatment for local anaesthetic
systemic toxicity (LAST) initially based on laboratory results in animal models with the …

Lipid emulsion in local anesthetic toxicity : Current Opinion in Anesthesiology Lipid emulsion
in local anesthetic toxicity : Current Opinion in Anesthesiology Log in or Register Subscribe to …

Intravenous lipid emulsion (ILE) has been suggested as a potential universal antidote for
cardiovascular and central nervous system toxicity resulting from a multitude of …

Introduction Clinicians utilize lipid emulsion to treat local anesthetic toxicity and non-local
anesthetic toxicities, a practice supported by animal experimentation and clinical …

Bupivacaine (BPV) can cause severe central nervous system toxicity when absorbed into
the blood circulation system. Rapid intravenous administration of lipid emulsion (LE) could …