Toxicity, biodegradation, and nutritional intervention mechanism of zearalenone

P Cai, S Liu, Y Tu, T Shan - Science of The Total Environment, 2024 - Elsevier
Zearalenone (ZEA), a global mycotoxin commonly found in a variety of grain products and
animal feed, causes damage to the gastrointestinal tract, immune organs, liver and …

Cupping therapy: An analysis of the effects of suction on skin and the possible influence on human health

DT Lowe - Complementary therapies in clinical practice, 2017 - Elsevier
Background Cupping therapy is a traditional therapy that has been employed worldwide for
thousands of years. Despite a lack of quality clinical studies evaluating the efficacy of …

Cordyceps cicadae Mycelia Ameliorate Cisplatin‐Induced Acute Kidney Injury by Suppressing the TLR4/NF‐κB/MAPK and Activating the HO‐1/Nrf2 and Sirt‐1 …

JS Deng, WP Jiang, CC Chen, LY Lee… - Oxidative medicine …, 2020 - Wiley Online Library
Acute kidney injury (AKI) is a common clinical problem, characterized by a sudden loss of
renal function, a high risk of death, and the eventual development of renal fibrosis and renal …

Protective effect of ferulic acid on cisplatin induced nephrotoxicity in rats

E Bami, OB Ozakpınar, ZN Ozdemir-Kumral… - Environmental …, 2017 - Elsevier
This study aims to determine the potential protective effects of ferulic acid against cisplatin-
induced nephrotoxicity and to compare its effect with curcumin, a well-known protective …

[HTML][HTML] Ameliorative effect of betulinic acid against zearalenone exposure triggers testicular dysfunction and oxidative stress in mice via p38/ERK MAPK inhibition …

X Lin, L Zhu, X Gao, L Kong, Y Huang, H Zhao… - Ecotoxicology and …, 2022 - Elsevier
Zearalenone (ZEA) is a nonsteroidal estrogenic mycotoxin, which mainly contaminates
grains and has estrogen-like effects on the reproductive system. Betulinic acid (BA), a …

Carvacrol attenuates acute kidney injury induced by cisplatin through suppression of ERK and PI3K/Akt activation

I Potočnjak, R Domitrović - Food and Chemical Toxicology, 2016 - Elsevier
We investigated the mechanisms of renoprotective effects of carvacrol, a monoterpenoid
compound, against cisplatin (CP)-induced kidney injury. Male BALB/cN mice were orally …

Oleanolic acid attenuates cisplatin-induced nephrotoxicity in mice and chemosensitizes human cervical cancer cells to cisplatin cytotoxicity

I Potočnjak, L Šimić, I Vukelić, R Domitrović - Food and chemical toxicology, 2019 - Elsevier
Oleanolic acid (OA) is a natural triterpenoid that possesses numerous beneficial health
effects such as antioxidant, anti-inflammatory and anti-apoptotic activities. In this study, we …

Stevia and stevioside protect against cisplatin nephrotoxicity through inhibition of ERK1/2, STAT3, and NF-κB activation

I Potočnjak, D Broznić, M Kindl, M Kropek… - Food and Chemical …, 2017 - Elsevier
We investigated the effect of natural sweetener Stevia rebaudiana and its constituent
stevioside in cisplatin (CP)-induced kidney injury. Male BALB/cN mice were orally …

Proximal tubule-targeted heme oxygenase-1 in cisplatin-induced acute kidney injury

S Bolisetty, A Traylor, R Joseph… - American Journal of …, 2016 - journals.physiology.org
Heme oxygenase-1 (HO-1) is a cytoprotective enzyme that catalyzes the breakdown of
heme to biliverdin, carbon monoxide, and iron. The beneficial effects of HO-1 expression are …

Dioscin ameliorates cisplatin-induced intestinal toxicity by mitigating oxidative stress and inflammation

S Jin, T Zhu, S Deng, D Li, J Li, X Liu, Y Liu - International …, 2022 - Elsevier
Cisplatin is the most widely prescribed drug in chemotherapy, but its gastrointestinal toxicity
reduces therapeutic efficacy. Oxidative stress and inflammation are considered to be the …