Artificial intelligence for cognitive health assessment: state-of-the-art, open challenges and future directions

AR Javed, A Saadia, H Mughal, TR Gadekallu… - Cognitive …, 2023 - Springer
The subjectivity and inaccuracy of in-clinic Cognitive Health Assessments (CHA) have led
many researchers to explore ways to automate the process to make it more objective and to …

The Effects of APOEe4 Allele on Cerebral Structure, Function, and Related Interactions with Cognition in Young Adults

L Kucikova, X Xiong, P Reinecke, J Madden… - Ageing Research …, 2024 - Elsevier
In the last decade, extensive research has emerged into understanding the impact of risk
factors for Alzheimer's Disease (AD) on brain in pre-symptomatic stages. We investigated …

[HTML][HTML] Source space connectomics of neurodegeneration: one-metric approach does not fit all

P Prado, S Moguilner, JA Mejía… - Neurobiology of …, 2023 - Elsevier
Brain functional connectivity in dementia has been assessed with dissimilar EEG
connectivity metrics and estimation procedures, thereby increasing results' heterogeneity. In …

Sensitive and reproducible MEG resting-state metrics of functional connectivity in Alzheimer's disease

DN Schoonhoven, CT Briels, A Hillebrand… - Alzheimer's Research & …, 2022 - Springer
Background Analysis of functional brain networks in Alzheimer's disease (AD) has been
hampered by a lack of reproducible, yet valid metrics of functional connectivity (FC). This …

The menstrual cycle alters resting-state cortical activity: a magnetoencephalography study

R Haraguchi, H Hoshi, S Ichikawa, M Hanyu… - Frontiers in human …, 2021 - frontiersin.org
Resting-state neural oscillations are used as biomarkers for functional diseases such as
dementia, epilepsy, and stroke. However, accurate interpretation of clinical outcomes …

Harmonized multi‐metric and multi‐centric assessment of EEG source space connectivity for dementia characterization

P Prado, JA Mejía, A Sainz‐Ballesteros… - Alzheimer's & …, 2023 - Wiley Online Library
Introduction Harmonization protocols that address batch effects and cross‐site
methodological differences in multi‐center studies are critical for strengthening …

[HTML][HTML] Tau pathology in early Alzheimer's disease is linked to selective disruptions in neurophysiological network dynamics

E Kocagoncu, A Quinn, A Firouzian, E Cooper… - Neurobiology of …, 2020 - Elsevier
Understanding the role of Tau protein aggregation in the pathogenesis of Alzheimer's
disease is critical for the development of new Tau-based therapeutic strategies to slow or …

Attenuated neural activity in processing decision-making feedback in uncertain conditions in patients with mild cognitive impairment

Y Zhang, M Zhang, L Wang, Y Zheng, H Li… - European Archives of …, 2024 - Springer
The present study aimed to explore the potential neural correlates during feedback
evaluation during decision-making under risk and ambiguity in MCI. Nineteen individuals …

Neurophysiological and brain structural markers of cognitive frailty differ from Alzheimer's disease

E Kocagoncu, D Nesbitt, T Emery… - Journal of …, 2022 - Soc Neuroscience
With increasing life span and prevalence of dementia, it is important to understand the
mechanisms of cognitive aging. Here, we focus on a subgroup of the population we term …

Neurophysiological trajectories in Alzheimer's disease progression

K Kudo, KG Ranasinghe, H Morise, F Syed, K Sekihara… - Elife, 2024 - elifesciences.org
Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β and misfolded
tau proteins causing synaptic dysfunction, and progressive neurodegeneration and …